TMEM215 (TM215_HUMAN) as a Drug Target and Biomarker (G401498)

Target Name: TMEM215

NCBI ID: G401498

TMEM215

Other Name(s): TM215_HUMAN | transmembrane protein 215 | Transmembrane protein 215

TMEM215 (TM215_HUMAN) as a Drug Target and Biomarker

TMEM215 (TM215_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the transmembrane protein family and is localized to the endoplasmic reticulum (ER) and the nuclear envelope (NE). TMEM215 plays a crucial role in various cellular processes, including the regulation of cell adhesion, migration, and the development of cancer. Its function has been extensively studied, and it has been identified as a potential drug target and biomarker.

Drug Target Potential

TMEM215 is a potential drug target due to its unique structure and its involvement in multiple cellular processes. One of the key features of TMEM215 is its extracellular domain, which consists of a long amino acid sequence that is involved in various interactions with other proteins, including cadherins and integrins. This domain has been shown to play a critical role in the regulation of cell adhesion and adiposity.

In addition to its extracellular domain, TMEM215 has a transmembrane region that is involved in the regulation of the passage of nutrients and waste products across the membrane. This region has been shown to be involved in the regulation of the production of various signaling molecules, including the TGF-β pathway.

TMEM215 has also been shown to be involved in the regulation of cell migration and the development of cancer. Its expression has been shown to be elevated in various types of cancer, including breast, ovarian, and prostate cancer. Additionally, TMEM215 has been shown to play a role in the regulation of the stem cell maintenance and the differentiation of cancer cells.

Biomarker Potential

TMEM215 has also been identified as a potential biomarker for various types of cancer. Its expression has been shown to be elevated in various types of cancer, including breast, ovarian, and prostate cancer. Additionally, TMEM215 has been shown to play a role in the regulation of the stem cell maintenance and the differentiation of cancer cells.

The Role of TMEM215 in Cancer

TMEM215 has been shown to play a critical role in the development and progression of cancer. Its expression has been shown to be elevated in various types of cancer, including breast, ovarian, and prostate cancer. Additionally, TMEM215 has been shown to play a role in the regulation of cell adhesion, migration, and the production of various signaling molecules, including the TGF-β pathway.

TMEM215 has also been shown to contribute to the development of cancer stem cells. Its expression has been shown to be elevated in various types of cancer, including breast, ovarian, and prostate cancer. Additionally, TMEM215 has been shown to play a role in the regulation of cell adhesion, migration, and the production of various signaling molecules, including the TGF-β pathway.

Conclusion

TMEM215 (TM215_HUMAN) is a protein that is expressed in various tissues of the human body and plays a crucial role in various cellular processes, including the regulation of cell adhesion, migration, and the development of cancer. Its unique structure and involvement in multiple cellular processes make it an attractive drug target and a potential biomarker for various types of cancer. Further research is needed to fully understand its role in cancer and its potential as a drug.

Protein Name: Transmembrane Protein 215

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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