TMEM213: A Transmembrane Protein as a Potential Drug Target and Biomarker

Target Name: TMEM213

NCBI ID: G155006

TMEM213

Other Name(s): transmembrane protein 213 | Transmembrane protein 213 | TM213_HUMAN

TMEM213: A Transmembrane Protein as a Potential Drug Target and Biomarker

Introduction

TMEM213 (Transmembrane Protein 213) is a protein that is expressed in various cell types of the human body, including neurons, endothelial cells, and epithelial cells. It plays a crucial role in the development, maintenance, and regulation of various physiological processes in the body. Unfortunately, despite its importance, TMEM213 has not yet been explored as a drug target or biomarker.

During the last decade, the study of transmembrane proteins (TMPs) has gained significant attention due to their involvement in various physiological processes and their potential as drug targets. TMPs are proteins that span the cell membrane and extend into the cytoplasm, playing a vital role in cell signaling, communication, and exocrine function. TMEM213 is one of these TMPs that has not yet been explored as a drug target or biomarker.

In this article, we will explore the biology of TMEM213, its potential drug target properties, and its potential as a biomarker for various diseases.

Biogenesis and Localization

TMEM213 is a member of the superfamily of transmembrane proteins (TMPs), which are characterized by the presence of a transmembrane region and cytoplasmic regions involved in various functions, such as intracellular signaling, protein-protein interactions, and cell signaling. TMEM213 is expressed in Various cell types of the human body, including neurons, endothelial cells, and epithelial cells. Its localization is primarily in the cytoplasm, where it is involved in various signaling pathways.

Function and Putative Functions

TMEM213 is involved in various signaling pathways that are essential for the development, maintenance, and regulation of neural circuits. One of its key functions is in the regulation of neuronal excitability, which is critical for the proper functioning of the nervous system. TMEM213 has been shown to play a role in the regulation of action potentials, the dynamics of intracellular signaling pathways, and the modulation of ion channels in neurons.

Additionally, TMEM213 is involved in the regulation of cell adhesion, migration, and the formation of tissues. Its localization in the cytoplasm allows it to be involved in various signaling pathways that regulate the movement and behavior of cells.

Potential Drug Target

TMEM213 has not yet been explored as a drug target, but its potential properties make it an attractive target for future research. The regulation of neuronal excitability and the maintenance of neural circuits are critical for the proper functioning of the nervous system, making TMEM213 a potential target for neurodegenerative diseases.

TMEM213 has been shown to interact with various signaling molecules, including tyrosine kinases, voltage-gated ion channels, and protein kinases. Its interaction with these molecules suggests that it may be a useful target for drugs that target neurodegenerative diseases.

In addition, TMEM213 has also been shown to play a role in the regulation of cancer cell growth and metastasis. Its localization in the cytoplasm and its involvement in various signaling pathways make it a potential target for anti-cancer drugs.

Potential Biomarkers

TMEM213 may also have potential as a biomarker for various diseases. Its involvement in various signaling pathways and its localization in the cytoplasm make it a potential target for various diseases, including neurodegenerative diseases, cancer, and diabetes.

Conclusion

In conclusion, TMEM213 is a transmembrane protein that is involved in various physiological processes in the human body. Despite its importance, TMEM213 has not yet been explored as a drug target or biomarker. The regulation of neuronal excitability, the maintenance of neural circuits, the Regulation of cell adhesion, migration, and the formation of tissues, and the regulation of cancer cell growth and metastasis are some of the potential functions of TMEM213. Further research is needed to determine its potential as a drug target and biomarker.

Protein Name: Transmembrane Protein 213

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•   expression level;
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