ARMCX1: GPCR Regulating TGF-βand NF-kappa-B Signaling Pathways

Target Name: ARMCX1

NCBI ID: G51309

ARMCX1

ARMCX1: GPCR Regulating TGF-βand NF-kappa-B Signaling Pathways

ARMCX1 (GASP7) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling.

GPCR signaling pathways involve the interaction between intracellular signaling molecules and the cytoplasmic environment. These interactions are mediated by the GPCRs, which are characterized by their transmembrane nature, their ability to couple to intracellular signaling molecules, and their involvement in a wide range of physiological processes.

ARMCX1 is a GPCR that is involved in the regulation of cellular signaling pathways, including inflammation, cell survival, and angiogenesis. It is a potent modulator of several intracellular signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway.

The TGF-β pathway is a critical pathway that is involved in the regulation of cellular growth, differentiation, and inflammation. This pathway is characterized by the production of transforminger factor beta (TGF-β), which is a cytokine that plays a central role in the regulation of cellular growth and differentiation.

ARMCX1 is a critical regulator of the TGF-β pathway, as it is able to inhibit the activity of the TGF-β receptor, which is the protein that binds to the TGF-β cytokine. This inhibition of TGF-β receptor activity allows ARMCX1 to prevent the uncontrolled growth and differentiation that can occur as a result of TGF-β signaling.

The PI3K/Akt pathway is a signaling pathway that is involved in the regulation of cellular signaling pathways, including cell survival and angiogenesis. This pathway is characterized by the production of phosphatidylinositol (PI), which is a signaling molecule that plays a central role in the regulation of various cellular processes, including cell survival and angiogenesis.

ARMCX1 is also a critical regulator of the PI3K/Akt pathway, as it is able to inhibit the activity of the PI3K enzyme, which is the protein that catalyzes the production of PI. This inhibition of PI3K enzyme activity allows ARMCX1 to prevent the uncontrolled growth and survival that can occur as a result of PI3K signaling.

The NF-kappa-B pathway is a signaling pathway that is involved in the regulation of cellular signaling pathways, including inflammation and cell survival. This pathway is characterized by the production of nuclear factor kappa B (NF-kappa-B), which is a protein that plays a central role in the regulation of various cellular processes, including inflammation and cell survival.

ARMCX1 is also a critical regulator of the NF-kappa-B pathway, as it is able to inhibit the activity of the NF-kappa-B enzyme, which is the protein that catalyzes the production of NF-kappa-B. This inhibition of NF-kappa-B enzyme activity allows ARMCX1 to prevent the uncontrolled inflammation and cell survival that can occur as a result of NF-kappa-B signaling.

In conclusion, ARMCX1 is a GPCR that is involved in the regulation of various cellular signaling pathways, including inflammation, cell survival, and angiogenesis. Its function as a modulator of these pathways is critical for the proper regulation of cellular processes and for the maintenance of cellular homeostasis. Further research is needed to fully understand the role of ARMCX1 in cellular signaling and its potential as a drug target or biomarker.

Protein Name: Armadillo Repeat Containing X-linked 1

Functions: Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1

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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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