SHC4: A Protein Target for Cancer and Neurodegenerative Diseases

Target Name: SHC4

NCBI ID: G399694

SHC4

SHC4: A Protein Target for Cancer and Neurodegenerative Diseases

SHC4, also known as hShcD, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell signaling, particularly in the regulation of cell proliferation and apoptosis.

Recent studies have identified SHC4 as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because SHC4 has been shown to play a role in the regulation of cellular processes that are often disrupted in these diseases, such as the regulation of cell proliferation, apoptosis, and inflammation.

One of the key mechanisms by which SHC4 regulates cell signaling is through its role in the regulation of the DNA damage response. This is a critical process that helps cells repair damage to their DNA, and it is often disrupted in cancer cells.

Research has shown that SHC4 plays a key role in the regulation of the DNA damage response by promoting the formation of a protein complex called the N-end rundown complex (NEC). This complex is composed of several proteins, including SHC4 itself, and it is responsible for the removal of damaged DNA from the cell.

Studies have also shown that SHC4 is involved in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death. This is a natural and important process that helps remove damaged or dysfunctional cells from the body, and it is often disrupted in diseases such as neurodegenerative disorders.

In addition to its role in cell signaling, SHC4 has also been shown to play a key role in the regulation of inflammation. This is because it is involved in the production of a type of immune cell called a T-cell, which is important for mount

Protein Name: SHC Adaptor Protein 4

Functions: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1

The "SHC4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHC4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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