CABP5: A Potential Drug Target and Biomarker for Calcium Homeostasis

Target Name: CABP5

NCBI ID: G56344

CABP5

CABP5: A Potential Drug Target and Biomarker for Calcium Homeostasis

Abstract:
Calcium homeostasis is a critical regulatory process that plays a crucial role in various physiological functions, including muscle contractions, nerve impulse conduction, and brain function. The calcium-binding protein (CABP) family is a large transmembrane protein that plays a central role in maintaining calcium homeostasis. CABP5, a member of the CABP family, has been identified as a potential drug target and biomarker for various diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease.

Introduction:
Calcium homeostasis is a complex process that involves multiple protein interactions and regulatory mechanisms. The regulation of calcium homeostasis is critical for various physiological functions, including muscle contractions, nerve impulse conduction, and brain function. The calcium-binding protein (CABP) family is a large transmembrane protein that plays a central role in maintaining calcium homeostasis. CABP5, a member of the CABP family, has been identified as a potential drug target and biomarker for various diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease.

CABP5: A Potential Drug Target:
CABP5 is a 21-kDa protein that is expressed in various tissues, including brain, heart, muscle, and pancreas. It is a member of the CABP family, which includes six structurally similar proteins: CABP1-CABP6. CABP5 has four transmembrane domains ( TMDs) and a short cytoplasmic tail. It has been shown to play a critical role in maintaining calcium homeostasis by regulating the activity of several calcium-dependent enzymes.

CABP5 has been shown to regulate the activity of several calcium-dependent enzymes, including calbindin (Ca2+- calibrating protein), parathyroid hormone (PTH), and calcitonin (CT). These enzymes are involved in various physiological processes, including bone growth and maintenance, neurotransmission, and hormone regulation. Therefore, CABP5 may be a potential drug target for diseases that are characterized by the disruption of calcium homeostasis.

CABP5 has also been shown to play a role in the regulation of cell adhesion and migration. It has been shown to interact with several cell adhesion molecules, including cadherin and E-cadherin, and to regulate their activity. This may have implications for the development of diseases that are characterized by the disruption of cell adhesion, such as cancer.

CABP5: A Potential Biomarker:
CABP5 has also been identified as a potential biomarker for various diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease. The disruption of calcium homeostasis has been implicated in the development of these diseases. Therefore, CABP5 may be a useful biomarker for the diagnosis and treatment of these diseases.

Alzheimer's disease is a progressive neurodegenerative disease characterized by the accumulation of neurofibrillary tangles and the loss of brain cells. The disruption of calcium homeostasis has been implicated in the development of Alzheimer's disease. Therefore, CABP5 may be a potential drug target or biomarker for the treatment of Alzheimer's disease.

Parkinson's disease is a progressive neurodegenerative disease characterized by the accumulation of neurofibrillary tangles and the loss of brain cells. The disruption of calcium homeostasis has been implicated in the development of Parkinson's disease. Therefore, CABP5 may be a potential drug target or biomarker for the treatment of Parkinson's disease.

CABP5 has also been shown to be involved in the regulation of cardiovascular function. It has been shown to regulate the activity of several enzymes involved in the regulation of calcium homeostasis, including cal

Protein Name: Calcium Binding Protein 5

Functions: Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials (By similarity). Involved in the transmission of light signals (By similarity). May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner (By similarity). May play a role in the extension and network organization of neurites (By similarity)

The "CABP5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CABP5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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