CA6: A Potential Drug Target and Biomarker for Various Diseases

Target Name: CA6

NCBI ID: G765

Content of Review Report on CA6 Target / Biomarker

CA6

CA6: A Potential Drug Target and Biomarker for Various Diseases

Carbonic anhydrase 6 (CA6) is a protein that is expressed in various tissues throughout the body. It is a key player in the regulation of cellular processes such as cell signaling, DNA replication, and cell death. The CA6 protein has been identified as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

CA6 is a member of the superfamily of ANPs (proteins that contain a nucleotide-binding oligomerization domain), which includes proteins that play a critical role in regulating DNA replication, transcription, and apoptosis. ANPs are characterized by a specific domain that contains a nucleotide -binding oligomerization (NBO) domain, which is responsible for binding to DNA in a specific sequence.

The NBO domain is a key feature of CA6, and it is responsible for the protein's ability to interact with DNA. This interaction is essential for CA6's function in regulating DNA replication and transcription. CA6 helps to ensure that the DNA template is properly copied and that the replicated DNA is stable.

In addition to its role in regulating DNA replication, CA6 is also involved in the regulation of cell signaling and cell death. It has been shown to play a role in the regulation of cell cycle progression, and it has been implicated in the development and progression of various cancers.

CA6 has also been identified as a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. For example, high levels of CA6 have been shown to be associated with the development of certain types of cancer, such as breast cancer and ovarian cancer. Additionally, elevated levels of CA6 have been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential clinical applications, CA6 is also of interest to researchers as a potential drug target. The NBO domain of CA6 makes it a promising target for small molecules and other compounds that can modulate its function. Several studies have shown that inhibitors of CA6 can be effective in treating various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In conclusion, CA6 is a protein that plays a critical role in regulating cellular processes throughout the body. Its function in regulating DNA replication and transcription, as well as its potential as a biomarker for various diseases, makes it an attractive target for small molecules and other compounds that can modulate its function. Further research is needed to fully understand the role of CA6 in the regulation of cellular processes and its potential as a drug target.

Protein Name: Carbonic Anhydrase 6

Functions: Reversible hydration of carbon dioxide. Its role in saliva is unknown

The "CA6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CA6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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