PLPP6: A Protein with Diverse Functions in Cytoskeleton and Cell Signaling

Target Name: PLPP6

NCBI ID: G403313

PLPP6

PLPP6: A Protein with Diverse Functions in Cytoskeleton and Cell Signaling

PLPP6 (poly (L-伪-glutamyl-proline) peptide-6) is a protein that is expressed in various tissues and cells in the body. It is made up of 11 amino acids and has been shown to have a variety of functions in both the cytoskeleton and the cell membrane.

One of the key functions of PLPP6 is its role in the cytoskeleton. PLPP6 is a component of the cytoskeleton, which is the structure that gives cells their shape and helps them maintain their structural integrity. The cytoskeleton is made up of a complex network of proteins that work together to keep cells in a specific shape and maintain their structural integrity. PLPP6 plays a key role in this network by helping to regulate the distribution of proteins within the cytoskeleton.

Another function of PLPP6 is its role in cell signaling. PLPP6 has been shown to be involved in a variety of signaling pathways, including the regulation of cell growth, differentiation, and survival. It has been shown to play a key role in the regulation of cell signaling by interacting with a variety of signaling proteins, including TGF-β1, a protein that is involved in cell growth and differentiation.

PLPP6 has also been shown to have a variety of potential drug targets. Its unique structure and the various functions it is involved in make it an attractive target for drug development. For example, PLPP6 has been shown to play a role in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. This makes it an potential target for drugs that are designed to promote or inhibit cell adhesion.

Additionally, PLPP6 has been shown to be involved in the regulation of cell signaling pathways that are involved in diseases such as cancer. Its involvement in these pathways makes it an potential target for drugs that are designed to inhibit the progression of cancer.

In conclusion, PLPP6 is a protein that has a variety of functions in both the cytoskeleton and the cell membrane. Its unique structure and the various functions it is involved in make it an attractive target for drug development. Further research is needed to fully understand the role of PLPP6 in the regulation of cell signaling and its potential as a drug target.

Protein Name: Phospholipid Phosphatase 6

Functions: Magnesium-independent polyisoprenoid diphosphatase that catalyzes the sequential dephosphorylation of presqualene, farnesyl, geranyl and geranylgeranyl diphosphates (PubMed:16464866, PubMed:19220020, PubMed:20110354). Functions in the innate immune response through the dephosphorylation of presqualene diphosphate which acts as a potent inhibitor of the signaling pathways contributing to polymorphonuclear neutrophils activation (PubMed:16464866, PubMed:23568778). May regulate the biosynthesis of cholesterol and related sterols by dephosphorylating presqualene and farnesyl diphosphate, two key intermediates in this biosynthetic pathway (PubMed:20110354). May also play a role in protein prenylation by acting on farnesyl diphosphate and its derivative geranylgeranyl diphosphate, two precursors for the addition of isoprenoid anchors to membrane proteins (PubMed:20110354). Has a lower activity towards phosphatidic acid (PA), but through phosphatidic acid dephosphorylation may participate in the biosynthesis of phospholipids and triacylglycerols (PubMed:18930839). May also act on ceramide-1-P, lysophosphatidic acid (LPA) and sphing-4-enine 1-phosphate/sphingosine-1-phosphate (PubMed:18930839, PubMed:20110354)

The "PLPP6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLPP6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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