PLTP: A Drug Target / Disease Biomarker (G5360)

Target Name: PLTP

NCBI ID: G5360

PLTP

PLTP: A Drug Target / Disease Biomarker

PLTP, or poly(lactic-co-glycolic acid), is a protein that is expressed in various tissues throughout the body. It is a key player in the regulation of cell signaling pathways, and has been shown to play a role in a variety of biological processes, including tissue repair, inflammation, and cancer progression. As a result, PLTP has generated a lot of interest as a potential drug target or biomarker.

One of the key advantages of PLTP is its ability to interact with a wide range of signaling pathways. PLTP has been shown to play a role in several signaling pathways that are important for both normal development and disease progression. For example, PLTP has been shown to be involved in the regulation of cell proliferation, differentiation, and inflammation. It has also been shown to be involved in the regulation of cell migration and the formation of tissues.

PLTP has also been shown to play a role in the regulation of immune responses. PLTP has been shown to be involved in the regulation of T cell development and function, and has been shown to play a role in the regulation of inflammation. This suggests that PLTP may be a useful target for drugs that are aimed at modulating immune responses.

Another potential advantage of PLTP is its ability to interact with a wide range of proteins. PLTP has been shown to interact with a wide range of proteins, including signaling proteins, cytoskeletal proteins, and transcription factors. This suggests that PLTP may be a useful target for drugs that are aimed at modulating protein interactions.

PLTP has also been shown to play a role in the regulation of cell signaling pathways in a variety of organisms, including humans. PLTP has been shown to play a role in the regulation of cell signaling pathways in development, growth, and repair. This suggests that PLTP may be a useful target for drugs that are aimed at modulating these processes.

In addition to its potential role in modulating signaling pathways, PLTP has also been shown to play a role in the regulation of cellular processes that are important for both normal development and disease progression. For example, PLTP has been shown to play a role in the regulation of cell division, cell growth, and cell differentiation. It has also been shown to play a role in the regulation of cell cycle progression and the regulation of DNA replication.

PLTP has also been shown to play a role in the regulation of inflammation. PLTP has been shown to play a role in the regulation of inflammatory responses, and has been shown to play a role in the regulation of cytokine production. This suggests that PLTP may be a useful target for drugs that are aimed at modulating inflammatory responses.

In conclusion, PLTP is a protein that has been shown to play a role in a variety of biological processes. As a result, PLTP has generated a lot of interest as a potential drug target or biomarker. Its ability to interact with a wide range of signaling pathways, as well as its ability to interact with a wide range of proteins, makes PLTP a promising target for drugs that are aimed at modulating these processes. Further research is needed to fully understand the role of PLTP in biology, and to determine the best way to use it as a drug.

Protein Name: Phospholipid Transfer Protein

Functions: Mediates the transfer of phospholipids and free cholesterol from triglyceride-rich lipoproteins (low density lipoproteins or LDL and very low density lipoproteins or VLDL) into high-density lipoproteins (HDL) as well as the exchange of phospholipids between triglyceride-rich lipoproteins themselves (PubMed:7654777, PubMed:9132017, PubMed:11013307, PubMed:19321130, PubMed:21515415, PubMed:29883800). Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylinositol, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine (PubMed:9132017). Plays an important role in HDL remodeling which involves modulating the size and composition of HDL (PubMed:29883800). Also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion (PubMed:21736953). Two distinct forms of PLTP exist in plasma: an active form that can transfer phosphatidylcholine from phospholipid vesicles to HDL, and an inactive form that lacks this capability (PubMed:11013307)

The "PLTP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLTP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets