Target Name: PLPPR1
NCBI ID: G54886
Review Report on PLPPR1 Target / Biomarker Content of Review Report on PLPPR1 Target / Biomarker
PLPPR1
Other Name(s): Plasticity-related gene 3 protein | Plasticity related gene 3 | RP11-35N6.1 | inactive 2-lysophosphatidate phosphatase PLPPR1 | LPPR1 | PRG3 | PLPPR1 variant 2 | Phospholipid phosphatase related 1, transcript variant 1 | Lipid phosphate phosphatase-related protein type 1 | Phospholipid phosphatase-related protein type 1 | lipid phosphate phosphatase-related protein type 1 | PLPR1_HUMAN | Phospholipid phosphatase related 1, transcript variant 2 | PRG-3 | plasticity related gene 3 | PLPPR1 variant 1 | plasticity-related gene 3 protein | phospholipid phosphatase related 1

PLPPR1: A Potential Drug Target for Cell Plasticity and Survival

PLPPR1 (Plasticity-related gene 1) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer, neurodegenerative diseases, and developmental disorders. The protein encoded by PLPPR1 is involved in the regulation of cell plasticity, which refers to the ability of cells to change and adapt to their environment.

PLPPR1 is a member of the TGF-β family of proteins, which are known for their role in promoting cell growth, differentiation, and survival. TGF-β signaling is a complex process that involves the interaction of multiple proteins, including PLPPR1. The plasticity of cells is regulated by the balance between the inhibitory and activating forms of TGF-β signaling.

PLPPR1 has been shown to play a role in the regulation of cell plasticity in various organisms, including humans. For example, studies have shown that PLPPR1 is involved in the development and maintenance of normal brain plasticity in children, and that it is a potential target for the treatment of neurodevelopmental disorders such as Alzheimer's disease and Parkinson's disease.

In addition to its role in cell plasticity, PLPPR1 has also been shown to play a role in the regulation of cell survival. Studies have shown that PLPPR1 is involved in the regulation of cell apoptosis, which is the process by which cells die when they have reached a certain level of stress or damage. This suggests that PLPPR1 may be a potential target for the treatment of diseases that are characterized by chronic cellular stress, such as cancer.

PLPPR1 has also been shown to play a role in the regulation of cell proliferation. Studies have shown that PLPPR1 is involved in the regulation of cell proliferation in various tissues and that it is a potential target for the treatment of diseases that are characterized by uncontrolled cell growth, such as cancer.

In conclusion, PLPPR1 is a gene that has the potential to be a drug target or biomarker for the treatment of various diseases. Further research is needed to fully understand the role of PLPPR1 in cell plasticity and its potential as a therapeutic target.

Protein Name: Phospholipid Phosphatase Related 1

Functions: May play a role in neurite outgrowth and neurogenesis

The "PLPPR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLPPR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2 | POF1B