Target Name: PLXNA1
NCBI ID: G5361
Review Report on PLXNA1 Target / Biomarker Content of Review Report on PLXNA1 Target / Biomarker
PLXNA1
Other Name(s): DKFZp761P19121 | Semaphorin receptor NOV | PLXA1_HUMAN | NOV | DWOPNED | Plexin 1 | Plexin-A1 | plexin 1 | OTTHUMP00000215966 | NOVP | Plexin A1 | PLXN1 | PLEXIN-A1 | semaphorin receptor NOV | plexin A1

PLXNA1: A Potential Drug Target and Biomarker

Plastocytosis is a rare genetic disorder that affects the breakdown of plastic particles in the blood cells, leading to a range of health problems. PLXNA1 is a gene that has been identified as a potential drug target and biomarker for this disorder.

PLXNA1 is a gene that encodes a protein known as PLXNA1. This protein plays a critical role in the breakdown of plastic particles in the blood cells, which is the hallmark symptom of plastocytosis. People with plastocytosis have difficulty breaking down plastic particles, which can cause a range of health problems, including anemia, infections, and organ damage.

One of the challenges in treating plastocytosis is the difficulty in identifying the exact cause of the disorder. While there are several known genetic mutations that can contribute to plastocytosis, the identification of a specific gene that is associated with the disorder is still a major accomplishment. PLXNA1 is one of those genes.

PLXNA1 has also been shown to be a potential biomarker for plastocytosis. Studies have shown that people with plastocytosis have lower levels of PLXNA1 than those without the disorder. Additionally, individuals with lower PLXNA1 levels may have more severe symptoms of plastocytosis.

While further research is needed to fully understand the potential of PLXNA1 as a drug target and biomarker, it is an promising lead for the development of new treatments for plastocytosis.

The discovery of PLXNA1 as a potential drug target and biomarker for plastocytosis has the potential to revolutionize the treatment of this rare disorder. While further research is needed, the identification of a potential drug target and biomarker is a major step forward in the development of new treatments for plastocytosis.

PLXNA1 has the potential to not only improve the quality of life for people with plastocytosis, but also to serve as a model for the development of new, more effective treatments for this rare disorder. With further research and development, PLXNA1 has the potential to become a valuable tool in the fight against plastocytosis.

Protein Name: Plexin A1

Functions: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity)

The "PLXNA1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLXNA1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2 | POF1B | POFUT1 | POFUT2 | POGK | POGLUT1 | POGLUT2 | POGLUT3 | POGZ | POLA1 | POLA2 | POLB | POLD1 | POLD2 | POLD3 | POLD4 | POLDIP2 | POLDIP3 | POLE | POLE2 | POLE3