Target Name: PLVAP
NCBI ID: G83483
Review Report on PLVAP Target / Biomarker Content of Review Report on PLVAP Target / Biomarker
PLVAP
Other Name(s): PV1 | Gp68 | DIAR10 | Fenestrated-endothelial linked structure protein; PV-1 protein | Plasmalemma vesicle-associated protein | plasmalemma vesicle protein 1 | Fenestrated-endothelial linked structure protein | PV-1 | plasmalemma vesicle associated protein | Fenestrated endothelial-linked structure protein | gp68 | fenestrated endothelial-linked structure protein | Plasmalemma vesicle protein 1 | fenestrated-endothelial linked structure protein; PV-1 protein | PLVAP_HUMAN | Plasmalemma vesicle associated protein | FELS | PV-1 protein

PLVAP: A Potential Cancer Target and Biomarker

PLVAP (poly (L-lysine)valine protamineuronucleotide) is a synthetic nucleotide that is derived from the amino acid lysine. As a glycosylation-modified nucleic acid molecule, PLVAP has important value in biomedical research and drug research. In recent years, with the increased expression of PLVAP in a variety of tumor cells, it has attracted much attention as a potential tumor target molecule.

The expression level of PLVAP changes in a variety of tumors, and its expression level is closely related to the aggressiveness and growth rate of the tumor. The expression level of PLVAP is also related to the drug resistance of tumor cells. When tumor cells become resistant to PLVAP, the expression level of PLVAP will change, thus affecting the growth and survival of tumor cells.

As a drug target molecule, PLVAP's role in tumor treatment has also attracted much attention. Some studies have shown that PLVAP can be used as a target molecule for tumor treatment, inhibiting the growth and spread of tumor cells by interfering with the expression of PLVAP. In addition, PLVAP can also be used as a tumor biomarker to predict the survival and treatment effect of tumor patients.

The chemical structure of PLVAP and its relationship with tumors have also attracted widespread research interest. The PLVAP molecule contains a glycosylated lysine residue, and this glycosylation modification plays an important role in the growth and invasion of tumor cells. In addition, the chemical structure of PLVAP also contains some other biologically active chemical groups, such as phosphate groups and methyl groups, which can affect the physical properties and biological activity of PLVAP.

In tumor research, the expression level, chemical structure and relationship of PLVAP with tumors have been extensively studied. These research results indicate that PLVAP, as a tumor target molecule and biomarker, has great potential for clinical application. Future research will mainly focus on in-depth research on the chemical structure, biological activity and relationship between PLVAP and tumors, in order to provide a theoretical basis for the clinical application of PLVAP in tumor treatment.

Protein Name: Plasmalemma Vesicle Associated Protein

Functions: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development

The "PLVAP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLVAP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2 | POF1B | POFUT1 | POFUT2 | POGK | POGLUT1 | POGLUT2 | POGLUT3 | POGZ | POLA1 | POLA2 | POLB | POLD1 | POLD2 | POLD3 | POLD4 | POLDIP2 | POLDIP3