Target Name: PLPPR3
NCBI ID: G79948
Review Report on PLPPR3 Target / Biomarker Content of Review Report on PLPPR3 Target / Biomarker
PLPPR3
Other Name(s): Phospholipid phosphatase-related protein type 3 (isoform 1) | phospholipid phosphatase related 3 | PLPPR3 variant 1 | PRG2 | plasticity-related gene 2 protein | PRG-2 | PLPR3_HUMAN | Plasticity-related gene 2 protein | lipid phosphate phosphatase-related protein type 3 | inactive phospholipid phosphatase PLPPR3 | Phospholipid phosphatase related 3, transcript variant 1 | PAP-2-like protein 2 | Lipid phosphate phosphatase-related protein type 3 | LPR3 | LPPR3 | Phospholipid phosphatase-related protein type 3

PLPPR3: A Potential Drug Target Or Biomarker

PLPPR3 (Phospholipid phosphatase-related protein type 3 (isoform 1)) is a protein that is expressed in various tissues and cells in the human body. It is a member of the PLPPR family of proteins, which are involved in the breakdown of phospholipids. This protein is of particular interest as a potential drug target or biomarker due to its involvement in a variety of cellular processes, including the regulation of cell signaling pathways and the maintenance of cellular structure.

PLPPR3 is a 120 amino acid protein that is localized to the endoplasmic reticulum (ER) and the cytoplasm. It is involved in the hydrolysis of phospholipids, which is the breaking down of the cell membrane to release its contents. This process is critical for the proper functioning of cells, including the regulation of signaling pathways and the maintenance of cellular structure. PLPPR3 is also involved in the regulation of cellular processes such as cell adhesion, migration and the cytoskeleton.

One of the key functions of PLPPR3 is its role in the regulation of the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cellular signaling and is a key regulator of many cellular processes, including cell growth, differentiation, and survival. PLPPR3 is known to be involved in the regulation of the PI3K/Akt signaling pathway by breaking down the phospholipid cardiolipin, which is a key component of the cell membrane.

In addition to its role in the regulation of the PI3K/Akt signaling pathway, PLPPR3 is also involved in the regulation of many other cellular processes. For example, it is involved in the regulation of cell adhesion by breaking down the phospholipid-coated diacylglycerol , which is a key component of the cell membrane. It is also involved in the regulation of cell migration by breaking down the phospholipid mimic receptor, which is a key component of the cell surface.

PLPPR3 is also involved in the regulation of cellular structure. It is known to be involved in the regulation of the cytoskeleton by breaking down the phospholipid tubulin, which is a key component of the cytoskeleton. This regulation of cytoskeleton is important for the proper functioning of cells and is involved in many cellular processes, including cell division, growth and the maintenance of cellular structure.

PLPPR3 is also of interest as a potential drug target or biomarker due to its involvement in the regulation of cellular signaling pathways and the maintenance of cellular structure. Many diseases, including cancer, are characterized by the disruption of normal cellular signaling pathways and the maintenance of cellular structure. Therefore, targeting PLPPR3 with drugs or other therapeutic agents that can modulate its function may be a promising strategy for the treatment of many diseases.

In conclusion, PLPPR3 is a protein that is involved in the regulation of various cellular processes, including the PI3K/Akt signaling pathway, cell adhesion, migration and cytoskeleton. It is of particular interest as a potential drug target or biomarker due to its involvement in the regulation of cellular signaling pathways and the maintenance of cellular structure. Further research is needed to fully understand the role of PLPPR3 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Phospholipid Phosphatase Related 3

The "PLPPR3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLPPR3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2 | POF1B | POFUT1 | POFUT2