MORF4L2: A Potential Drug Target Or Biomarker (G9643)

Target Name: MORF4L2

NCBI ID: G9643

MORF4L2

MORF4L2: A Potential Drug Target Or Biomarker

MORF4L2 (MSL3-2 protein), also known as ALDH1129087, is a protein that is expressed in a variety of tissues and cells in the human body. It is a member of the ATP-binding costeroid receptor (ABCR) gene family, which is responsible for regulating various cellular processes, including metabolism, inflammation, and signaling pathways.

MORF4L2 has been identified as a potential drug target or biomarker due to its involvement in multiple cellular processes that are associated with various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the most significant functions of MORF4L2 is its role in the detoxification of xenobiotics, such as drugs and environmental toxins, which are often harmful to the human body. Xenobiotics can cause oxidative stress and inflammation in the body, leading to a host of cellular and molecular changes that can contribute to the development of various diseases. By detecting and removing xenobiotics from the body, MORF4L2 may have a potential to reduce the risk of oxidative stress and inflammation, which can in turn reduce the risk of disease.

MORF4L2 is also involved in the regulation of cellular signaling pathways, including the TGF-β pathway. TGF-β is a well-known signaling pathway that is involved in various cellular processes, including cell growth, differentiation, and inflammation. MORF4L2 has been shown to play a role in regulating TGF-β activity, which may have implications for the development of TGF-β-related diseases.

In addition to its involvement in cellular signaling pathways, MORF4L2 is also involved in the regulation of cellular processes that are important for maintaining tissue homeostasis. This includes the regulation of ion balance, which is critical for maintaining the proper pH and ionic composition of tissues. MORF4L2 has been shown to play a role in regulating ion balance in various tissues, including the brain and the liver.

MORF4L2 has also been identified as a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that MORF4L2 is overexpressed in various tissues and cells that are affected by cancer, including breast cancer and colorectal cancer. This may suggest that MORF4L2 may be a useful biomarker for the detection and diagnosis of these diseases.

In addition to its potential as a drug target or biomarker, MORF4L2 is also of interest to researchers because of its unique structure and biology. MORF4L2 is a member of the ABCR gene family, which is characterized by the presence of a specific zinc finger motif in its amino acid sequence. This motif is thought to play a role in the regulation of various cellular processes, including protein function and stability.

While more research is needed to fully understand the role of MORF4L2 in cellular processes and its potential as a drug target or biomarker, its potential impact on the development of various diseases makes it a promising area of study. Further research is likely to shed light on the mechanisms of MORF4L2's function in the body and its potential as a therapeutic target or biomarker.

Protein Name: Mortality Factor 4 Like 2

Functions: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones

The "MORF4L2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MORF4L2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets