GGNBP1: A Potential Drug Target and Biomarker (G449520)
GGNBP1: A Potential Drug Target and Biomarker
Gametogenetin binding protein 1 (GGNBP1) is a gene that encodes a protein located in the germ cell-specific gene cluster (GSC) in the human genome. GSNPs, also known as pseudogenes, are genomic regions that are usually transcribed but not translated into proteins. GGNBP1 is one of the many GSNPs that have been identified and studied, and it has gained significant interest due to its potential involvement in various biological processes.
GGNBP1 is a 21-kDa protein that is expressed in various tissues and cells of the body, including testes, ovaries, brain, and heart. It is characterized by a unique N-terminus that is specific to GSCs and a C-terminus that is similar to that of other GSNPs. The middle region of the protein contains a conserved domain that is involved in protein-protein interactions and is responsible for GGNBP1's stability and localization to various cellular compartments.
GGNBP1 has been shown to play a critical role in several biological processes that are important for male fertility and development, including germ cell formation, meiosis, and fertilization. In addition, GGNBP1 has also been implicated in various diseases, including cancer, neurodegenerative diseases, and developmental disorders.
GGNBP1 has also been identified as a potential drug target and biomarker. The high-throughput screening approach has identified several small molecules that interact with GGNBP1 and have the potential to be repurposed for therapeutic purposes. One of the most promising compounds is called GNBP-101, which is a small molecule that binds to GGNBP1 with high affinity and selectivity. GnRH agonists, which are used to treat infertility, have also been shown to increase GnRH release, which could potentially enhance the effectiveness of GnRH agonists in treating infertility.
Another compound that has been shown to interact with GGNBP1 is called YAP/TAZ, a protein that is involved in various cellular signaling pathways, including the regulation of cell growth, differentiation, and survival. YAP/TAZ has been shown to interact with GGNBP1 and enhance the activity of GnRH, which could potentially contribute to the efficacy of GnRH agonists in treating infertility.
In addition, GGNBP1 has also been shown to be involved in the regulation of neuronal excitability and synaptic plasticity. GSNPs have been shown to play a critical role in the regulation of neuronal excitability and synaptic plasticity, and it is possible that GGNBP1 may be involved in these processes as well.
GGNBP1 is a gene that has the potential to be a drug target and biomarker. The studies on GGNBP1 have identified several potential therapeutic compounds that have the potential to treat various diseases, including infertility, cancer, and neurodegenerative diseases. Further research is needed to fully understand the role of GGNBP1 in these diseases and to develop effective therapies.
Protein Name: Gametogenetin Binding Protein 1 (pseudogene)
Functions: May be involved in spermatogenesis
The "GGNBP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GGNBP1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
GGNBP2 | GGPS1 | GGT1 | GGT2P | GGT3P | GGT5 | GGT6 | GGT7 | GGT8P | GGTA1 | GGTLC1 | GGTLC2 | GGTLC3 | GH1 | GH2 | GHDC | GHITM | GHR | GHRH | GHRHR | GHRL | GHRLOS | GHSR | GID4 | GID8 | GIGYF1 | GIGYF2 | GIHCG | GIMAP1 | GIMAP1-GIMAP5 | GIMAP2 | GIMAP3P | GIMAP4 | GIMAP5 | GIMAP6 | GIMAP7 | GIMAP8 | GIMD1 | GIN1 | GINM1 | GINS complex | GINS1 | GINS2 | GINS3 | GINS4 | GIP | GIPC1 | GIPC2 | GIPC3 | GIPR | GIT1 | GIT2 | GJA1 | GJA10 | GJA1P1 | GJA3 | GJA4 | GJA5 | GJA8 | GJA9 | GJA9-MYCBP | GJB1 | GJB2 | GJB3 | GJB4 | GJB5 | GJB6 | GJB7 | GJC1 | GJC2 | GJC3 | GJD2 | GJD3 | GJD4 | GK | GK2 | GK3 | GK5 | GKAP1 | GKN1 | GKN2 | GKN3P | GLA | GLB1 | GLB1L | GLB1L2 | GLB1L3 | GLC1C | GLCCI1 | GLCCI1-DT | GLCE | GLDC | GLDN | GLE1 | GLG1 | GLI1 | GLI2 | GLI3 | GLI4 | GLIDR
