PEBP1: A Potential Drug Target and Biomarker for Phosphatidylamide Binding Protein-1

Target Name: PEBP1

NCBI ID: G5037

PEBP1

PEBP1: A Potential Drug Target and Biomarker for Phosphatidylamide Binding Protein-1

Abstract:

Phosphatidylethanolamine-binding protein (PEBP1) is a protein that has been identified as a potential drug target and biomarker. PEBP1 is involved in various cellular processes, including cell signaling, inflammation, and neurodegeneration. Its function as a protein-protein interaction partner has led to its potential as a drug target. In this article, we will discuss the structure and function of PEBP1, its potential drug targets, and its role as a biomarker for various diseases.

Introduction:

PEBP1, also known as PIP4K2, is a protein that is expressed in various cell types, including neurons, macrophages, and astrocytes. PEBP1 is a member of the phosphatidylinositol (PI) signaling pathway, which is a well-established signaling pathway that regulates various cellular processes, including cell signaling, inflammation, and neurodegeneration.

Structure and Function:

PEBP1 has a molecular weight of approximately 42 kDa and consists of 111 amino acid residues. It has a distinct N-terminal and C-terminal region, with a catalytic active center located in the middle of the protein. The catalytic active center is composed of a nucleotide base and a phosphate group, which are important for protein-protein interaction.

PEBP1 functions as a protein-protein interaction partner, which means it can interact with other proteins to regulate various cellular processes. One of the well-known functions of PEBP1 is its role in the regulation of the PI signaling pathway. PEBP1 has been shown to interact with various components of the PI signaling pathway, including PIK3CA, PIK3C, and PKA.

PEBP1 has also been shown to play a role in the regulation of inflammation and neurodegeneration. It has been shown to be involved in the regulation of various cellular processes that are involved in inflammation and neurodegeneration, including the regulation of pain perception, inflammation, and neurotoxicity.

Drug Targets:

PEBP1 has been identified as a potential drug target due to its involvement in various cellular processes that are involved in disease. One of the potential drug targets for PEBP1 is its role in the regulation of pain perception. PEBP1 has been shown to play a role in the regulation of pain perception and has been shown to interact with various pain receptors, including N-methyl-D-aspartate (NMDA) receptors.

PEBP1 has also been shown to be involved in the regulation of inflammation and neurodegeneration. It has been shown to play a role in the regulation of various cellular processes that are involved in inflammation and neurodegeneration, including the regulation of pain perception, inflammation, and neurotoxicity.

PEBP1 has also been shown to be involved in the regulation of cell signaling, including the regulation of cell growth, differentiation, and survival. It has been shown to play a role in the regulation of various cellular processes that are involved in cell signaling, including the regulation of cell growth, differentiation, and survival.

Biomarkers:

PEBP1 has also been identified as a potential biomarker for various diseases. One of the potential biomarkers for PEBP1 is its involvement in the regulation of pain perception. PEBP1 has been shown to play a role in the regulation of pain perception and has been shown to interact with various pain receptors, including N-methyl-D-aspartate (NMDA) receptors.

PEBP1 has also been shown to be involved in the regulation of inflammation and neurodegeneration. It has been shown to play a role in the regulation of various cellular processes that are involved in inflammation and neurodegeneration, including the regulation of pain perception, inflammation, and neurotoxicity.

Conclusion:

PEBP1 is a protein that has been identified as a potential drug target and biomarker. Its function as a protein-protein interaction partner has led to its potential as a drug target. We have discussed the structure and function of PEBP1, its potential drug targets, and its role as a biomarker for various diseases. Further research is needed to fully understand the role of PEBP1 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Phosphatidylethanolamine Binding Protein 1

Functions: Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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