PFN3: A Potential Drug Target Or Biomarker for Various Diseases

Target Name: PFN3

NCBI ID: G345456

PFN3

PFN3: A Potential Drug Target Or Biomarker for Various Diseases

Profilin-3 (PFN3) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the profilin family, which includes proteins that play a critical role in the regulation of protein-protein interactions and in the regulation of cellular processes such as cell adhesion, migration, and survival.

PFN3 is a 12-kDa protein that is expressed in the brain, heart, kidneys, and liver. It is highly conserved across species, with only minor differences in its amino acid sequence between different species. PFN3 is localized to the cytoplasm and has been shown to interact with various cellular signaling pathways, including the TGF-β pathway.

One of the most interesting aspects of PFN3 is its ability to interact with the protein known as profilin-2 (PF2), which is also a member of the profilin family. PF2 is also expressed in various tissues throughout the body and has been shown to play a critical role in the regulation of cellular processes such as cell adhesion, migration, and survival.

The interaction between PFN3 and PF2 has been shown to play a critical role in the regulation of cellular processes that are important for the development and maintenance of tissues and organs. For example, studies have shown that the interaction between PFN3 and PF2 is critical for the regulation of cell adhesion and the development of tissues that are organized in a specific order, such as the development of tissues that line the body's surfaces.

In addition to its role in the regulation of cell adhesion and tissue organization, PFN3 has also been shown to play a critical role in the regulation of cellular signaling pathways. For example, studies have shown that PFN3 can interact with various signaling proteins and that its interaction with these proteins can modulate the activity of these proteins. This suggests that PFN3 may be a drug target or biomarker for various diseases.

PFN3 has also been shown to play a critical role in the regulation of cellular processes that are important for the maintenance of cellular homeostasis. For example, studies have shown that PFN3 can interact with various ion channels and that its interaction with these channels can modulate the activity of these channels. This suggests that PFN3 may be a drug target or biomarker for diseases that are characterized by abnormal ion channels or their dysfunction.

In conclusion, PFN3 is a protein that is expressed in various tissues throughout the body and has been shown to play a critical role in the regulation of cellular processes that are important for the development, maintenance, and homeostasis of tissues and organs. Its interaction with the protein known as profilin-2 (PF2) has been shown to play a critical role in the regulation of cellular signaling pathways and in the regulation of cell adhesion and tissue organization. These properties make PFN3 a potential drug target or biomarker for various diseases. Further research is needed to fully understand the role of PFN3 in the regulation of cellular processes and its potential as a drug or biomarker.

Protein Name: Profilin 3

Functions: Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis

The "PFN3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PFN3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets