Target Name: PFKFB4
NCBI ID: G5210
Review Report on PFKFB4 Target / Biomarker Content of Review Report on PFKFB4 Target / Biomarker
PFKFB4
Other Name(s): Fructose-2,6-bisphosphatase | PFKFB4 variant 1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 6-phosphofructo-2-kinase | 6PF-2-K/Fru-2,6-P2ase testis-type isozyme | 6PF-2-K/Fru-2,6-P2ase 4 | Bifunctional enzyme with kinase and biphosphatase activities | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, transcript variant 1 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform b | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform a | bifunctional enzyme with kinase and biphosphatase activities | PFK/FBPase 4 | PFKFB4 variant 2 | F264_HUMAN | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, transcript variant 2 | 6PF-2-K/Fru-2,6-P2ASE testis-type isozyme | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

PKB/PKC: A Versatile Enzyme Involved in Cellular Signaling and Metabolism

Fructose-2,6-bisphosphatase (PKB/PKC) is a protein that plays a crucial role in cellular signaling and metabolism. It is a key enzyme in the fructose pathway, which is a critical pathway for the production of energy from glucose. PKB/PKC is involved in the regulation of many cellular processes, including cell growth, differentiation, and metabolism.

PKB/PKC is a protein that is expressed in many different cell types, including muscle, nerve, and heart cells. It is also highly expressed in the liver, where it is involved in the metabolism of glucose and other nutrients. PKB/PKC is a versatile enzyme that can be used as a drug target or biomarker in a variety of diseases.

One of the key functions of PKB/PKC is its role in the regulation of cellular signaling pathways. PKB/PKC is involved in the regulation of many different signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. These pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and metabolism.

PKB/PKC is also involved in the regulation of cell adhesion and migration. It is a key enzyme in the production of adhesion molecules, which are involved in the stickiness of cells to other cells and the formation of tissues. PKB/PKC is also involved in the regulation of cell migration, which is essential for the development and progression of tissues and organs.

PKB/PKC is also involved in the regulation of cellular energy metabolism. It is a key enzyme in the citric acid cycle, which is the primary energy-producing pathway in cells. PKB/PKC is involved in the production of ATP, which is the energy currency of the cell.

PKB/PKC is also involved in the regulation of cell signaling pathways that are involved in inflammation and immune response. It is a key enzyme in the production of pro-inflammatory cytokines, which are involved in the regulation of inflammation and immune response.

In conclusion, PKB/PKC is a versatile enzyme that is involved in a wide range of cellular processes. It is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of PKB/PKC in cellular signaling and metabolism.

Protein Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

Functions: Synthesis and degradation of fructose 2,6-bisphosphate

The "PFKFB4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PFKFB4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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