Regulation of Proteasome Degradation By Profilin-4 (G375189)

Target Name: PFN4

NCBI ID: G375189

PFN4

Regulation of Proteasome Degradation By Profilin-4

Proteasome-mediated degradation is a ubiquitous process that is involved in the regulation of protein function and levels in the cells. It is a critical process that helps maintain cellular homeostasis and is also involved in the development and progression of many diseases. One of the key The proteins involved in this process is profilin-4 (PF4), which is a key regulator of the proteasome.

PF4 is a protein that is expressed in many different tissues and cells, including muscle, nerve, and epithelial cells. It is a 21 kDa protein that is composed of a N-terminal alpha helix, a middle alpha helix, and a C-terminal carboxy-terminal peptide. PF4 is involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and survival.

One of the key functions of PF4 is its role in the regulation of the proteasome. The proteasome is a complex that is responsible for degrading proteins in the cells. It is composed of a core protein and a nucleotide that is attached to the protein. core protein is the most abundant protein in the proteasome and is responsible for the formation of the nucleotide-protein complex. PF4 is involved in the regulation of the formation and stability of this complex, as well as its dynamics and stability.

PF4 is also involved in the regulation of the degradation of the proteasome. Degradation of the proteasome is critical for maintaining cellular homeostasis and for the regulation of many cellular processes, including cell growth, differentiation, and apoptosis. PF4 is involved in the regulation of the Degradation of the proteasome by the 26S proteasome, which is the most abundant form of the proteasome.

PF4 is also involved in the regulation of protein interactions and is a key regulator of the protein-protein interaction (PPI) network. PPIs are important for the regulation of cellular processes, including cell growth, differentiation, and survival. PF4 is involved in the regulation of PPIs by the protein tyrosine phosphatase (PTP), which is a key regulator of the PPI network.

PF4 is also involved in the regulation of cellular signaling pathways. It is involved in the regulation of many signaling pathways, including the TGF-β pathway, the Wnt pathway, and the Hedgehog pathway. PF4 is involved in the regulation of these pathways by the transforming growth factor beta (TGF-β), which is a key regulator of cellular signaling pathways.

PF4 is also involved in the regulation of inflammation and is a key regulator of the inflammasome. The inflammasome is a complex that is involved in the regulation of inflammation and is composed of the protein caspase-1, the protein palmitoyl-proteinase (P-PPT ), and the protein inflammasome precursor (IPI). PF4 is involved in the regulation of the inflammasome by the production of reactive oxygen species (ROS), which are important for the regulation of inflammation.

PF4 is also involved in the regulation of the DNA damage response. It is involved in the regulation of DNA damage repair pathways by the protein Checkpoint kinase (CHK). PF4 is involved in the regulation of CHK by the DNA damage repair protein Ku70.

PF4 is also involved in the regulation of the cell cycle. It is involved in the regulation of the G1 phase of the cell cycle and is involved in the production of the protein p21 (CDK4). PF4 is involved in the regulation of p21 by the protein p21-associated protein (p21AP), which is a

Protein Name: Profilin Family Member 4

Functions: Involved in male fertility. Required for manchette development and acrosome biogenesis during spermiogenesis (By similarity). Binds in vitro to phospholipids, including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA) (PubMed:19419568). Contrary to other profilin family members, does not bind to actin in vitro (PubMed:19419568)

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•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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