Study on ZFP26: RNA-NP Interactions and Cancer Treatment (G50862)

Study on ZFP26: RNA-NP Interactions and Cancer Treatment

RNA-Nucleic Acid-Protein (RNA-NP) interactions play a crucial role in various cellular processes, including gene regulation, DNA replication, and RNA splicing. RNA-binding proteins (RBPs) in RNA-NP interactions are an important class of proteins that participate in regulating gene expression and cell biological processes by binding to specific regions in DNA or RNA molecules. Among them, nucleolus-associated RNA-binding protein (RNP) is a special type of RBP that mainly plays a role in eukaryotic cells.

RNP family proteins include many types, among which nucleolus-associated RNA-binding proteins (RNPs) are a special type of RNP that mainly play a role in eukaryotic cells. RNP-RBP interaction is an important component of RNA-NP interaction and mediates the regulation process of gene expression.

ZFP26 is a nucleolus-associated RNA-binding protein that plays an important role in eukaryotic cells. ZFP26 can bind to specific regions in DNA and RNA molecules, including RNA-binding domain (RBD) and DNA-binding domain (DBD). By binding to DNA and RNA molecules, ZFP26 can regulate gene expression and participate in biological processes such as cell cycle regulation and DNA damage repair.

The biological functions and drug target properties of ZFP26 have aroused extensive research interest. Many studies have shown that ZFP26 plays an important role in various cancers, such as lung cancer, liver cancer, breast cancer, etc. The expression level of ZFP26 is positively correlated with the prognosis of cancer. Therefore, studying the biological functions and drug target properties of ZFP26 is of great significance for cancer treatment.

As a research hotspot on RNA-NP interactions, the drug target properties of ZFP26 have attracted widespread attention. Many studies have attempted to reveal the biological functions of ZFP26 and explore its possibility as a drug target. Currently, a variety of drugs that inhibit ZFP26 expression have entered clinical research, such as inhibitor of nuclear kernel-related RNA-binding protein (INP) drugs. These drugs provide new ideas for cancer treatment by inhibiting the biological functions of ZFP26.

In addition, some studies have also attempted to reveal the relationship between the biological functions of ZFP26 and drug targets. For example, some studies have shown that the biological function of ZFP26 is positively correlated with the expression level of PD-L1, and the expression level of PD-L1 is closely related to tumor immune evasion. Therefore, studying the interaction between ZFP26 and PD-L1 provides new ideas for tumor immunotherapy.

As an RNA-NP, ZFP26 plays an important role in cell biological processes. By studying the biological functions and drug target properties of ZFP26, new ideas and strategies for cancer treatment can be provided. With the deepening of research on ZFP26, we are expected to reveal more functions of ZFP26 in the fields of biology and medicine, bringing good news to human health.

Protein Name: Ring Finger Protein 141

Functions: May be involved in spermatogenesis

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More Common Targets

RNF144A | RNF144B | RNF145 | RNF146 | RNF148 | RNF149 | RNF150 | RNF151 | RNF152 | RNF157 | RNF157-AS1 | RNF165 | RNF166 | RNF167 | RNF168 | RNF169 | RNF17 | RNF170 | RNF175 | RNF180 | RNF181 | RNF182 | RNF183 | RNF185 | RNF186 | RNF187 | RNF19A | RNF19B | RNF2 | RNF20 | RNF207 | RNF208 | RNF212 | RNF212B | RNF213 | RNF213-AS1 | RNF214 | RNF215 | RNF216 | RNF216-IT1 | RNF216P1 | RNF217 | RNF217-AS1 | RNF220 | RNF222 | RNF224 | RNF225 | RNF227 | RNF24 | RNF25 | RNF26 | RNF31 | RNF32 | RNF32-DT | RNF34 | RNF38 | RNF39 | RNF4 | RNF40 | RNF41 | RNF43 | RNF44 | RNF5 | RNF5P1 | RNF6 | RNF7 | RNF7P1 | RNF8 | RNFT1 | RNFT2 | RNGTT | RNH1 | RNLS | RNMT | RNPC3 | RNPC3-DT | RNPEP | RNPEPL1 | RNPS1 | RNPS1P1 | RNR1 | RNR2 | RNU1-1 | RNU1-100P | RNU1-108P | RNU1-11P | RNU1-134P | RNU1-18P | RNU1-3 | RNU1-31P | RNU1-32P | RNU1-36P | RNU1-38P | RNU1-4 | RNU1-42P | RNU1-55P | RNU1-61P | RNU1-63P | RNU1-72P | RNU1-73P