Target Name: PHF7
NCBI ID: G51533
Review Report on PHF7 Target / Biomarker Content of Review Report on PHF7 Target / Biomarker
PHF7
Other Name(s): HSPC226 | PHF7_HUMAN | testicular secretory protein Li 34 | PHF7 variant 1 | PHD finger protein 7 (isoform 1) | Testis development protein NYD-SP6 | NYD-SP6 | PHD finger protein 7 | testis development protein NYD-SP6 | HSPC045

PHF7: A Protein Targeted for Drug Development

PHF7, also known as HSPC226, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a heat-spreading protein, which means that it tends to have a higher temperature than surrounding cells. This property is unique and is of interest in the context of disease, as warmer temperatures can contribute to the development and progression of certain diseases.

PHF7 has also been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique expression pattern and temperature-mediated properties have made it an attractive target for researchers to investigate.

One of the key features of PHF7 is its temperature-regulated structure.PHF7 is a member of the heat shock protein (HSP) family, which are known for their ability to withstand high temperatures.PHF7 is able to maintain a stable structure at high temperatures, which is unusual for a protein. This stability is important for its function, as it allows PHF7 to function as a drug target in a variety of ways.

One of the ways that PHF7 functions as a drug target is through its role in cell signaling.PHF7 has been shown to play a role in several signaling pathways, including the TGF-β pathway and the Wnt pathway. These pathways are involved in a variety of processes in the cell, including cell growth, differentiation, and survival. By participating in these pathways, PHF7 is able to influence the behavior of cells and contribute to the development of certain diseases.

Another way that PHF7 functions as a drug target is through its role in the immune system.PHF7 has been shown to play a role in the regulation of immune cell function, including the activation and proliferation of T cells. This is important for the immune system's ability to fight off infections and diseases, and PHF7's role in this system is a potential target for drugs that are designed to treat autoimmune disorders.

In addition to its role in cell signaling and immune function, PHF7 has also been shown to be involved in the development and progression of certain diseases. For example, PHF7 has been shown to be overexpressed in the brains of individuals with Alzheimer's disease, a neurodegenerative disorder. This suggests that PHF7 may be a potential drug target for treatments for this disorder.

Furthermore, PHF7 has also been shown to be involved in the regulation of pain.PHF7 has been shown to play a role in the regulation of pain signaling in the brain, which is important for the body's ability to perceive and respond to pain. This suggests that PHF7 may be a potential drug target for treatments of chronic pain.

In conclusion, PHF7 is a protein that has been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique temperature-regulated structure and its involvement in cell signaling, immune function, and pain regulation make it an attractive target for researchers to investigate. Further studies are needed to fully understand the role of PHF7 in disease and to identify potential drugs that can target it.

Protein Name: PHD Finger Protein 7

Functions: May play a role in spermatogenesis

The "PHF7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHF7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PHF8 | PHGDH | PHGR1 | PHIP | PHKA1 | PHKA1-AS1 | PHKA2 | PHKA2-AS1 | PHKB | PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO | PIGP | PIGQ | PIGR | PIGS | PIGT | PIGU | PIGV