Target Name: PHKB
NCBI ID: G5257
Review Report on PHKB Target / Biomarker Content of Review Report on PHKB Target / Biomarker
PHKB
Other Name(s): Phosphorylase kinase beta-subunit | Phosphorylase b kinase regulatory subunit beta | Phosphorylase kinase regulatory subunit beta, transcript variant 2 | Phosphorylase kinase subunit beta | phosphorylase kinase, beta | FLJ41698 | phosphorylase kinase beta-subunit | PHKB variant 2 | Phosphorylase kinase, beta | KPBB_HUMAN | phosphorylase kinase subunit beta | OTTHUMP00000164134 | DKFZp781E15103 | Phosphorylase b kinase regulatory subunit beta (isoform b) | PHKB variant 1 | phosphorylase kinase regulatory subunit beta | Phosphorylase kinase, beta polypeptide | Phosphorylase kinase regulatory subunit beta, transcript variant 1 | Phosphorylase kinase, beta (PHKB) | Phosphorylase b kinase regulatory subunit beta (isoform a)

PHKB: A Potent Inhibitor of PI3K/Akt Signaling

PHKB (Phosphorylase kinase beta-subunit) is a protein that is expressed in various tissues and cells throughout the body. It plays a crucial role in the regulation of cell growth, differentiation, and metabolism.PHKB is a key enzyme in the PI3K/Akt signaling pathway, which is a well-established pathway that regulates many cellular processes, including cell survival, proliferation, and angiogenesis.

The PI3K/Akt signaling pathway is a complex protein-protein interaction network that involves the interaction of various protein kinases, phosphatidylinositol (PI) molecules, and other signaling molecules.PHKB is one of the key enzymes in this network, and it plays a critical role in the generation of the signals that regulate cellular processes.

PHKB is a protein that is expressed in various tissues and cells throughout the body, including muscle, liver, and brain. It is primarily localized to the cytoplasm of these cells and is involved in the regulation of cellular processes such as cell adhesion, migration, and survival.

PHKB is a potent inhibitor of the PI3K/Akt signaling pathway. It can inhibit the activity of the AKT protein, which is a key component of the PI3K/Akt signaling pathway. This inhibition of the PI3K/Akt pathway can lead to the inhibition of cellular processes that are dependent on this pathway, such as cell growth, survival, and angiogenesis.

PHKB is also known as PIKB (phosphorylase kinase beta), and it is a protein that is involved in the regulation of many cellular processes. It is a key enzyme in the PI3K/Akt signaling pathway and is involved in the generation of the signals that regulate cellular processes such as cell adhesion, migration, and survival.

PHKB is a potent inhibitor of the PI3K/Akt signaling pathway. It can inhibit the activity of the AKT protein, which is a key component of the PI3K/Akt signaling pathway. This inhibition of the PI3K/Akt pathway can lead to the inhibition of cellular processes that are dependent on this pathway, such as cell growth, survival, and angiogenesis.

In addition to its role in the PI3K/Akt signaling pathway, PHKB is also involved in the regulation of many other cellular processes. For example, it is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs.PHKB is also involved in the regulation of cell migration, which is the process by which cells move from one location to another in the body.

PHKB is a protein that is involved in the regulation of many cellular processes. It is a key enzyme in the PI3K/Akt signaling pathway and is involved in the generation of signals that regulate cellular processes such as cell adhesion, migration, and survival.

In conclusion, PHKB is a protein that is involved in the regulation of many cellular processes. It is a key enzyme in the PI3K/Akt signaling pathway and is involved in the generation of signals that regulate cellular processes such as cell adhesion, migration, and survival. As a result, PHKB is a potential drug target and could be used as a biomarker for the diagnosis and treatment of various diseases.

Protein Name: Phosphorylase Kinase Regulatory Subunit Beta

Functions: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation

The "PHKB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHKB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO | PIGP | PIGQ | PIGR | PIGS | PIGT | PIGU | PIGV | PIGW | PIGX | PIGY | PIGZ | PIH1D1 | PIH1D2 | PIK3AP1 | PIK3C2A | PIK3C2B