Target Name: SERPINF2
NCBI ID: G5345
Review Report on SERPINF2 Target / Biomarker Content of Review Report on SERPINF2 Target / Biomarker
SERPINF2
Other Name(s): serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | serpin family F member 2 | Serpin family F member 2, transcript variant 3 | Plasmin inhibitor | Alpha-2-PI | alpha-2-plasmin inhibitor | Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | PLI | Alpha-2-antiplasmin (isoform b) | serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | Alpha-2-antiplasmin (isoform a) | Alpha-2-antiplasmin | A2AP | A2AP_HUMAN | alpha-2-AP | SERPINF2 variant 3 | Serpin F2 | plasmin inhibitor | Serine (or cysteine) proteinase inhibitor, clade F member 2 | Alpha-2-AP | serpin F2 | AAP | ALPHA-2-PI | alpha2AP | Alpha-2-plasmin inhibitor | Serpin family F member 2, transcript variant 1 | Serpin family F member 2, transcript variant 2 | Serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | SERPINF2 variant 2 | API | SERPINF2 variant 1

SERPINF2: A Potential Drug Target and Biomarker

SERPINF2, or serpin-related intracellular protein-2, is a protein that is expressed in various cell types of the human body. It is a member of the serpin family, which is a group of non-catalytic proteins that regulate the interactions between proteins and the extracellular matrix (ECM). The serpins function by forming a covalent complex with their target proteins, which in turn modulates their activity and stability.

SERPINF2 is a 21-kDa protein that is expressed in various tissues of the body, including the heart, lungs, kidneys, and liver. It is primarily localized to the endoplasmic reticulum (ER), where it is involved in the regulation of protein-protein interactions and in the assembly of protein-nucleic acid hybrids. SERPINF2 has also been shown to play a role in the regulation of cell adhesion, migration, and invasion.

One of the most significant aspects of SERPINF2 is its potential as a drug target. The serpin family has been identified as a promising drug target due to its involvement in various cellular processes that are crucial for human health and disease. The serpins have been shown to be involved in the regulation of blood clotting, inflammation, and pain perception. Therefore, targeting SERPINF2 could potentially lead to the development of new therapeutic approaches for a variety of diseases.

SERPINF2 has also been identified as a potential biomarker for several diseases. The serpin family has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Therefore, the levels of SERPINF2 in tissues or fluids, such as blood or urine, could be potential biomarkers for these diseases.

In conclusion, SERPINF2 is a protein that has significant implications as a drug target and biomarker. Further research is needed to fully understand its role in various cellular processes and its potential as a therapeutic approach for diseases.

Protein Name: Serpin Family F Member 2

Functions: Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin

The "SERPINF2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SERPINF2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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