Target Name: TAPBPL
NCBI ID: G55080
Review Report on TAPBPL Target / Biomarker Content of Review Report on TAPBPL Target / Biomarker
TAPBPL
Other Name(s): FLJ10143 | TAPBPR | Tapasin-related protein | tapasin-like | TAP binding protein like | TAPBP-R | TAPASIN-R | TAPBPL variant 1 | TAP-binding protein-related protein | Tapasin-related protein (isoform 1) | Tapasin-like | TPSNR_HUMAN | TAP binding protein like, transcript variant 1 | TAP-binding protein-like | TAP binding protein related

TAPBPL: A Potential Drug Target and Biomarker for FLJ10143, a Potential Treatment for Fibromyalgia

Abstract:

Fibromyalgia is a chronic widespread pain disorder characterized by muscle, tendon, and joint pain, widespread fatigue, and sleep disturbances. The prevalence of fibromyalgia is increasing, and its impact on quality of life is significant. Although there are several medications available for treating fibromyalgia, the disease remains untreated and underdiagnosed. TAPBPL, a novel gene expressed in the liver, has been identified as a potential drug target and biomarker for FLJ10143, a drug that may provide a new treatment option for patients with fibromyalgia.

Introduction:

Fibromyalgia is a chronic pain disorder that can cause significant disability and impact quality of life. The pain is typically widespread and constant, and can affect all parts of the body. Fibromyalgia is often associated with other chronic conditions, such as depression, anxiety, and sleep disorders. Despite the increasing awareness of fibromyalgia, the underlying causes of the disease are not well understood, and there are no approved treatments available.

Recent studies have identified several potential drug targets for fibromyalgia. One of these targets is TAPBPL, a gene expressed in the liver that has not been previously identified as a potential drug target. TAPBPL has been shown to play a role in the regulation of inflammation, and has been linked to the development of fibromyalgia.

The Importance of TAPBPL in Fibromyalgia:

TAPBPL is a gene that has not been studied extensively, but its potential role in fibromyalgia is significant. Fibromyalgia is characterized by the activation of immune cells, including T cells, which release cytokines that contribute to the development and maintenance of the disease. TAPBPL has been shown to play a role in the regulation of cytokine production and has been linked to the regulation of immune cell function.

FLJ10143, a Potential Drug Target:

FLJ10143 is a gene that has been shown to encode a protein that is involved in the regulation of inflammation and cytokine production. It has been shown to play a role in the development of fibromyalgia and has been linked to the development of other chronic conditions, such as rheumatoid arthritis and inflammatory bowel disease.

The Potential Benefits of TAPBPL and FLJ10143:

The identification of TAPBPL and FLJ10143 as potential drug targets for fibromyalgia provides a new direction in the development of treatments for this chronic and debilitating disorder. If successful, these treatments may provide a significant improvement in the quality of life for patients with fibromyalgia.

Conclusion:

TAPBPL is a gene that has not been previously identified as a potential drug target for fibromyalgia. However, its potential role in the regulation of inflammation and cytokine production makes it an attractive target for future research. The identification of FLJ10143 as a potential drug target for fibromyalgia provides a new direction in the development of treatments for this chronic and debilitating disorder. Further research is needed to determine the effectiveness of TAPBPL and FLJ10143 as potential drug targets for fibromyalgia.

Protein Name: TAP Binding Protein Like

Functions: Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC)

The "TAPBPL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TAPBPL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TAPT1 | TAPT1-AS1 | TARBP1 | TARBP2 | TARDBP | TARDBPP1 | TARDBPP3 | TARID | TARM1 | TARP | TARS1 | TARS2 | TARS3 | TAS1R1 | TAS1R2 | TAS1R3 | TAS2R1 | TAS2R10 | TAS2R13 | TAS2R14 | TAS2R16 | TAS2R19 | TAS2R20 | TAS2R3 | TAS2R30 | TAS2R31 | TAS2R38 | TAS2R39 | TAS2R4 | TAS2R40 | TAS2R41 | TAS2R42 | TAS2R43 | TAS2R45 | TAS2R46 | TAS2R5 | TAS2R50 | TAS2R60 | TAS2R63P | TAS2R64P | TAS2R7 | TAS2R8 | TAS2R9 | TASL | TASOR | TASOR2 | TASP1 | Taste receptor type 2 | Taste Receptors Type 1 | TAT | TAT-AS1 | TATDN1 | TATDN2 | TATDN2P3 | TATDN3 | TAX1BP1 | TAX1BP3 | TBATA | TBC1D1 | TBC1D10A | TBC1D10B | TBC1D10C | TBC1D12 | TBC1D13 | TBC1D14 | TBC1D15 | TBC1D16 | TBC1D17 | TBC1D19 | TBC1D2 | TBC1D20 | TBC1D21 | TBC1D22A | TBC1D22A-AS1 | TBC1D22B | TBC1D23 | TBC1D24 | TBC1D25 | TBC1D26 | TBC1D27P | TBC1D28 | TBC1D29P | TBC1D2B | TBC1D3 | TBC1D30 | TBC1D31 | TBC1D32 | TBC1D3B | TBC1D3C | TBC1D3F | TBC1D3G | TBC1D3H | TBC1D3L | TBC1D3P1 | TBC1D3P2 | TBC1D4 | TBC1D5 | TBC1D7 | TBC1D8 | TBC1D8-AS1