PRKCH: A Potential Drug Target and Biomarker for Diseases (G5583)

Target Name: PRKCH

NCBI ID: G5583

PRKCH

PRKCH: A Potential Drug Target and Biomarker for Diseases

PRKCH (PRKCH-L), also known as PKC-L, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of cell survival and growth, and has been linked to a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Recent studies have suggested that PRKCH may be a promising drug target for a variety of diseases. Because it is involved in many different cellular processes, it is potential to target multiple mechanisms of action, which could make it an effective treatment for a wide range of conditions.

One of the key reasons why PRKCH has the potential to be a drug target is its involvement in the regulation of cell survival and growth. PRKCH is a key regulator of the Wnt signaling pathway, a critical pathway that helps cells maintain their structure and function. When Wnt signaling is activated, PRKCH is activated and helps to regulate the growth and survival of cells.

Studies have shown that PRKCH is involved in the regulation of many different cellular processes, including cell division, migration, and angiogenesis (the formation of new blood vessels). In addition, PRKCH has been shown to play a role in the regulation of inflammation, which is a critical part of many diseases, including cancer.

Another potential reason why PRKCH may be a good drug target is its involvement in the regulation of cellular signaling pathways. PRKCH is a key regulator of the TGF-β pathway, which is involved in the regulation of cell growth, differentiation, and inflammation. The TGF-β pathway is a critical pathway that is involved in many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In addition, PRKCH has been shown to play a role in the regulation of cellular signaling pathways that are involved in diseases such as diabetes, hypertension, and heart failure. These diseases have a significant impact on public health and morbidity, and targeting PRKCH as a drug target may be a promising approach to treating these conditions.

PRKCH is also a potential biomarker for some diseases. The regulation of cellular processes is a critical part of many diseases, and changes in cellular processes can be used as biomarkers for these conditions. PRKCH has been shown to be involved in the regulation of many different cellular processes, which makes it a potential biomarker for a wide range of diseases.

In conclusion, PRKCH (PKC-L) is a protein that is expressed in various tissues throughout the body that is involved in the regulation of cell survival and growth, and has been linked to a number of diseases. Its potential as a drug target and biomarker make it an attractive target for research in the field of pharmacology. Further studies are needed to fully understand its role in the regulation of cellular processes and its potential as a drug and biomarker.

Protein Name: Protein Kinase C Eta

Functions: Product of an upstream open reading frame (ORF) of PRKCH which regulates translation of the downstream protein kinase C eta (PKC-eta) ORF (PubMed:19797084, PubMed:34593629). Functions as a repressive element that maintains low basal levels of PKC-eta in growing cells but enhances its expression during stress conditions induced by amino acid starvation in a EIF2AK4/GCN2-dependent manner (PubMed:19797084, PubMed:34593629). In addition to its role in regulating PKC-eta translation, also inhibits the kinase activity of PKC-eta as well as other protein kinases including PRKCD, PRKCQ and PRKCE but not PRKCA, PRKCG or PRKCZ (PubMed:34593629)

The "PRKCH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRKCH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets