VPS37D: A Protein Involved in Cell Biology and Disease (G155382)

Target Name: VPS37D

NCBI ID: G155382

VPS37D

VPS37D: A Protein Involved in Cell Biology and Disease

VPS37D (VP37D_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the superfamily of immediate-early gene (SEG) proteins, which are known for their ability to transcribe into RNA and be rapidly translated into proteins. VPS37D is a 21-kDa protein that is expressed in the brain, heart, and skeletal muscles.

The protein encoded by the VPS37D gene is highly conserved across various species, which suggests that it is a highly conserved protein that has been preserved over evolutionary time. The VPS37D protein has a calculated pI of 11.9 nM, which suggests that it is a protein that is relatively hydrophilic and can be easily dissolved in aqueous environments.

VPS37D is involved in various physiological processes in the human body. For example, it is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. VPS37D is also involved in the regulation of the cytoskeleton, which is the structure that gives cells shape and stability.

In addition to its role in cell biology, VPS37D is also a potential drug target. Many diseases, including neurodegenerative disorders, are characterized by the misfolding of proteins and the formation of aggregates that are harmful to the cell. VPS37D is thought to be involved in the regulation of protein folding and may be a target for therapeutic interventions aimed at preventing protein misfolding and aggregate formation.

VPS37D is also a potential biomarker for various diseases. For example, it is potentially involved in the development of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Additionally, VPS37D may be involved in the development of cardiovascular disease, as it has been shown to be expressed in the hearts of individuals with hypertension.

In conclusion, VPS37D (VP37D_HUMAN) is a protein that is expressed in various tissues of the human body and is involved in various physiological processes, including cell adhesion and cytoskeleton regulation. It is also a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of VPS37D in human physiology and disease.

Protein Name: VPS37D Subunit Of ESCRT-I

Functions: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation

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•   general information;
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•   expression level;
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