Target Name: VPS25
NCBI ID: G84313
Review Report on VPS25 Target / Biomarker Content of Review Report on VPS25 Target / Biomarker
VPS25
Other Name(s): dermal papilla-derived protein 9 | vacuolar protein sorting 25 homolog | ELL-associated protein of 20 kDa | ESCRT-II complex subunit VPS25 | FAP20 | EAP20 | DERP9 | VPS25_HUMAN | Dermal papilla-derived protein 9 | hVps25 | Vacuolar protein-sorting-associated protein 25 | Vacuolar protein sorting 25 homolog

VPS25: A Potential Drug Target and Biomarker

V PS25 (dermal papilla-derived protein 9) is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. VPS25 is a 25-kDa protein that is expressed in various tissues, including skin, hair, nails, and connective tissues. It is composed of a single chain of 25 amino acids and has a calculated pI of 5.5.

Potential Drug Target

VPS25 has been identified as a potential drug target due to its various functions in the cell. One of its functions is the regulation of cell growth, which is crucial for the development and progression of many diseases. In addition, VPS25 has been shown to play a role in cell-cell adhesion, which is important for the maintenance of tissue structure and function.

Another potential drug target for VPS25 is its role in the regulation of the immune response. VPS25 has been shown to interact with various immune cells, including T cells and natural killer cells, and has been shown to regulate the production of antibodies.

Biomarker

VPS25 has also been identified as a potential biomarker for various diseases. For example, VPS25 has been shown to be downregulated in various tissues and has been associated with the development of cancer. In addition, VPS25 has been shown to be elevated in the blood of individuals with neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease.

Conclusion

In conclusion, VPS25 is a protein that has potential as a drug target and biomarker for various diseases. Its functions in cell growth, cell-cell adhesion, and the immune response make it an attractive target for drug development. Further research is needed to fully understand the role of VPS25 in these diseases and to develop effective treatments.

Protein Name: Vacuolar Protein Sorting 25 Homolog

Functions: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses

The "VPS25 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VPS25 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

VPS26A | VPS26AP1 | VPS26B | VPS26C | VPS28 | VPS29 | VPS33A | VPS33B | VPS35 | VPS35L | VPS36 | VPS37A | VPS37B | VPS37C | VPS37D | VPS39 | VPS41 | VPS45 | VPS4A | VPS4B | VPS50 | VPS51 | VPS51P8 | VPS52 | VPS53 | VPS54 | VPS72 | VPS8 | VPS9D1 | VPS9D1-AS1 | VRK1 | VRK2 | VRK3 | VRTN | VSIG1 | VSIG10 | VSIG10L | VSIG10L2 | VSIG2 | VSIG4 | VSIG8 | VSIR | VSNL1 | VSTM1 | VSTM2A | VSTM2A-OT1 | VSTM2B | VSTM2B-DT | VSTM2L | VSTM4 | VSTM5 | VSX1 | VSX2 | VTA1 | VTCN1 | VTI1A | VTI1B | VTN | VTRNA1-1 | VTRNA1-2 | VTRNA1-3 | VTRNA2-1 | VTRNA3-1P | VWA1 | VWA2 | VWA3A | VWA3B | VWA5A | VWA5B1 | VWA5B2 | VWA7 | VWA8 | VWC2 | VWC2L | VWCE | VWDE | VWF | VXN | WAC | WAC-AS1 | WAKMAR1 | WAKMAR2 | WAPL | WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P