VPS28: A Potential Drug Target and Biomarker (G51160)

Target Name: VPS28

NCBI ID: G51160

VPS28

VPS28: A Potential Drug Target and Biomarker

VPS28, a viral protein that belongs to the VP220 family, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug has piqued the interest of pharmaceutical companies.

The VP220 family is a group of proteins that are characterized by their unique structure and the ability to cleave double-stranded DNA. These proteins have been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The VPS28 protein is a member of this family and is expressed in various tissues and organs, including the brain, spinal cord, and retina.

One of the unique features of the VPS28 protein is its ability to interact with double-stranded DNA. This interaction is critical for the protein's function, as it allows the protein to recognize and cleave specific DNA sequences. The VPS28 protein has been shown to interact with the double-stranded DNA in various tissues and has been implicated in various diseases, including cancer.

Research has shown that VPS28 is involved in the regulation of gene expression and has been implicated in the development and progression of various diseases. For example, studies have shown that VPS28 is involved in the regulation of gene expression in cancer cells and has been shown to promote the growth and survival of cancer cells.

In addition to its role in disease, the VPS28 protein has also been shown to have potential as a drug target. Studies have shown that VPS28 can be targeted by small molecules and has a unique expression profile that makes it a potential target for drug development. The VPS28 protein is also known to have a high degree of cross-reactivity, which means that it can be targeted by a variety of small molecules and may be a useful anchor for developing new drugs.

The potential of VPS28 as a drug target is further supported by its expression in various tissues and organs, including the brain, spinal cord, and retina. The brain is a particularly attractive target for drug development, as it is home to a large number of protein kinases and is involved in many critical cellular processes. The VPS28 protein has been shown to interact with several kinases, including PKA, kinase A1 (KOA1), and FAK. These interactions suggest that VPS28 may be a useful target for drugs that target protein kinases.

In addition to its potential as a drug target, the VPS28 protein has also been shown to be a potential biomarker for various diseases. The protein is expressed in various tissues and organs and has been shown to be involved in the regulation of gene expression. This suggests that VPS28 may be a useful biomarker for diseases that are characterized by changes in gene expression.

The potential of VPS28 as a drug target and biomarker is likely to continue to grow as research into the protein continues. Studies are being conducted to investigate the effects of small molecules on VPS28 expression and to determine its potential as a drug target. As research continues , the potential of VPS28 as a drug target and biomarker will be further validated, and its utility as a new drug or diagnostic tool will be further established.

In conclusion, VPS28 is a unique and promising protein that has potential as a drug target and biomarker. Its interaction with double-stranded DNA and its expression in various tissues and organs make it an attractive target for research into the protein's role in disease. Further research is needed to fully understand the potential of VPS28 as a drug and to determine its utility as a biomarker.

Protein Name: VPS28 Subunit Of ESCRT-I

Functions: Component of the ESCRT-I complex, a regulator of vesicular trafficking process

The "VPS28 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VPS28 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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