Target Name: ISY1
NCBI ID: G57461
Review Report on ISY1 Target / Biomarker Content of Review Report on ISY1 Target / Biomarker
ISY1
Other Name(s): FSAP33 | ISY1-RAB43 readthrough | Pre-mRNA-splicing factor ISY1 homolog | ISY1 splicing factor homolog | ISY1 variant 1 | ISY1 splicing factor homolog, transcript variant 1 | ISY1_HUMAN | ISY1-RAB43 protein | KIAA1160 | pre-mRNA-splicing factor ISY1 homolog | Pre-mRNA-splicing factor ISY1 homolog (isoform 1) | functional spliceosome-associated protein 33

Targeting ISY1: Developing Therapies and Diagnostic Tests

ISY1 (FSAP33) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and lungs. It is a member of the PDGF receptor family, which is a critical signaling pathway that regulates cell growth, differentiation, and survival. ISY1 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, ISY1 has become a focus of interest in drug development, as potential therapeutic approaches may target this protein to interfere with its abnormal expression or function.

One approach to targeting ISY1 is to use small molecules that can modulate its activity. One class of small molecules that have been shown to interact with ISY1 is called NEDD8-activating enzymes (NAEs). NEDD8 is a protein that can modify the activity of ISY1 , and NAEs are enzymes that add a NEDD8 atom to ISY1. By using NEDD8-activating enzymes to modify ISY1 activity, researchers have been able to develop potential drug candidates that can inhibit its growth or promote its degradation.

Another approach to targeting ISY1 is to use antibodies that recognize and label the protein. One class of antibodies that have been developed to target ISY1 is called Fc-trap antibodies. Fc-trap antibodies are designed to bind to a specific protein, such as ISY1 , and can be used to detect and label the protein in various tissues and cellular samples. These antibodies can be used in a variety of applications, including cell-based assays, mass spectrometry, and imaging.

In addition to these therapeutic approaches, researchers have also been interested in using ISY1 as a biomarker to diagnose and monitor various diseases. ISY1 has been shown to be expressed in a variety of tissues and has been associated with the development of various diseases, including cancer , neurodegenerative diseases, and autoimmune disorders. As a result, researchers have been interested in developing ISY1-based diagnostic tests and therapies that can detect and monitor these diseases at an early stage.

One approach to developing ISY1-based diagnostic tests is to use antibodies that recognize and label ISY1 in various tissues and cellular samples. These antibodies can then be used to detect the protein in a variety of biological samples, including blood, saliva, urine, and tissue samples. By using these tests, researchers have been able to monitor the levels of ISY1 in various tissues and detect the presence of ISY1-positive samples in a variety of diseases.

Another approach to developing ISY1-based therapies is to use small molecules that can modulate ISY1 activity. As mentioned earlier, NEDD8-activating enzymes have been shown to modify ISY1 activity, and NAEs can be used to develop potential drug candidates that target ISY1. By using these enzymes to modify ISY1 activity, researchers have been able to develop small molecules that can inhibit its growth or promote its degradation. These small molecules can then be tested for their potential therapeutic effects in a variety of applications, including cancer, neurodegenerative diseases, and autoimmune disorders.

In conclusion, ISY1 (FSAP33) is a protein that has been shown to play a critical role in the development and progression of various diseases. As a result, ISY1 has become a focus of interest in drug development, as potential therapeutic approaches may target this protein to intervene in its abnormal expression or function. ISY1 has also been used as a biomarker to diagnose and monitor various diseases, and researchers are interested in developing ISY1-based diagnostic tests and therapies that can detect and monitor these diseases at an early stage. With further research and development, ISY1 may turn out to be a valuable drug target and a promising area for

Protein Name: ISY1 Splicing Factor Homolog

The "ISY1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ISY1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ISY1-RAB43 | ISYNA1 | ITCH | ITFG1 | ITFG2 | ITFG2-AS1 | ITGA1 | ITGA10 | ITGA11 | ITGA2 | ITGA2B | ITGA3 | ITGA4 | ITGA5 | ITGA6 | ITGA6-AS1 | ITGA7 | ITGA8 | ITGA9 | ITGAD | ITGAE | ITGAL | ITGAM | ITGAV | ITGAX | ITGB1 | ITGB1BP1 | ITGB1BP2 | ITGB1P1 | ITGB2 | ITGB2-AS1 | ITGB3 | ITGB3BP | ITGB4 | ITGB5 | ITGB6 | ITGB7 | ITGB8 | ITGBL1 | ITIH1 | ITIH2 | ITIH3 | ITIH4 | ITIH5 | ITIH6 | ITK | ITLN1 | ITLN2 | ITM2A | ITM2B | ITM2C | ITPA | ITPK1 | ITPK1-AS1 | ITPKA | ITPKB | ITPKB-IT1 | ITPKC | ITPR1 | ITPR1-DT | ITPR2 | ITPR3 | ITPRID1 | ITPRID2 | ITPRIP | ITPRIPL1 | ITPRIPL2 | ITSN1 | ITSN2 | IVD | IVL | IVNS1ABP | IWS1 | IYD | IZUMO1 | IZUMO1R | IZUMO2 | IZUMO4 | JADE1 | JADE2 | JADE3 | JAG1 | JAG2 | JAGN1 | JAK1 | JAK2 | JAK3 | JAKMIP1 | JAKMIP1-DT | JAKMIP2 | JAKMIP2-AS1 | JAKMIP3 | JAM2 | JAM3 | JAML | Janus Kinase | JARID2 | JAZF1 | JAZF1-AS1 | JCAD