KL8: A Potential Drug Target and Biomarker for Various Diseases

Target Name: KLHL8

NCBI ID: G57563

KLHL8

KL8: A Potential Drug Target and Biomarker for Various Diseases

Kelch-like protein 8 (ISOform 1), also known as KL8, is a protein that is expressed in various tissues and cells in the human body. It is a member of the Kelch family of proteins, which are involved in various cellular processes, including cell signaling and cytoskeletal organization. KL8 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The Kelch family of proteins was first identified in the 1970s by researchers who showed that they were involved in the regulation of cell signaling pathways. The Kelch proteins are characterized by the presence of a catalytic domain, a transmembrane region, and a cytoplasmic tail. They are involved in a wide range of cellular processes, including the regulation of cytoskeletal organization, cell signaling, and cell division.

KL8 is a member of the Kelch family of proteins and is expressed in various tissues and cells in the human body. It is characterized by the presence of a catalytic domain, a transmembrane region, and a cytoplasmic tail. KL8 is involved in a wide range of cellular processes, including the regulation of cytoskeletal organization, cell signaling, and cell division.

One of the key functions of KL8 is its role in cell signaling. KL8 is involved in the regulation of several signaling pathways, including the T-cell signaling pathway, the G-protein-coupled receptor (GPCR) signaling pathway, and the insulin signaling pathway. KL8 has been shown to play a key role in the regulation of these signaling pathways and is potential drug targets for diseases that are characterized by the disruption of these signaling pathways.

In addition to its role in cell signaling, KL8 is also involved in the regulation of cytoskeletal organization. KL8 is a component of the cytoskeleton and is involved in the regulation of cell

Protein Name: Kelch Like Family Member 8

Functions: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN

The "KLHL8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLHL8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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