SLC13A1: A Potential Drug Target for Neurotransmitter Regulation and Cellular Processes

Target Name: SLC13A1

NCBI ID: G6561

SLC13A1

SLC13A1: A Potential Drug Target for Neurotransmitter Regulation and Cellular Processes

SLC13A1 (SLC13A1 variant 1) is a gene that encodes a protein known as solute carrier family 13 member 1 (SLC13A1). The SLC13A1 protein is a primary structure protein that is expressed in many different tissues and cells in the human body. It is involved in the transport of a variety of molecules, including ions, nutrients, and waste products.

One of the unique aspects of the SLC13A1 protein is its structure. It is made up of 1,862 amino acids and has a calculated molecular mass of 21.4 kDa. The protein has a single transmembrane segment and a single cytoplasmic tail. It is characterized by a number of unique features, including a N-terminal region that is rich in amino acids and a C-terminal region that is rich in cysteine residues.

SLC13A1 is a protein that is expressed in many different tissues and cells in the human body. It is highly expressed in the brain, where it is found in the basal ganglia, the cerebellum, and the retina. It is also expressed in other tissues, including the heart, the lungs, and the kidneys.

SLC13A1 is involved in the transport of a variety of molecules, including ions, nutrients, and waste products. It is particularly well-known for its role in the transport of sodium ions (Na+) across the blood-brain barrier. SLC13A1 is also involved in the transport of other ions, including potassium ions (K+), calcium ions (Ca2+), and magnesium ions (Mg2+).

SLC13A1 has also been shown to play a role in a variety of cellular processes. For example, it has been shown to be involved in the regulation of neurotransmitter release from neurons, the maintenance of cell volume and the regulation of pain perception.

SLC13A1 is also a potential drug target. Researchers have identified a number of potential drug candidates that are designed to interact with SLC13A1. These drugs have the potential to treat a variety of conditions, including neurological and psychiatric disorders.

In conclusion, SLC13A1 is a protein that is involved in the transport of a variety of molecules across the cell membrane. It is a potential drug target and may be a useful biomarker for a variety of diseases. Further research is needed to fully understand the role of SLC13A1 in the human body and to develop effective treatments for the conditions that it is involved in.

Protein Name: Solute Carrier Family 13 Member 1

Functions: Sodium:sulfate symporter that mediates sulfate reabsorption in the kidney and small intestine (PubMed:11161786). Can also mediate the transport of selenate and thiosulfate (By similarity)

The "SLC13A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC13A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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