Target Name: TMPRSS3
NCBI ID: G64699
Review Report on TMPRSS3 Target / Biomarker Content of Review Report on TMPRSS3 Target / Biomarker
TMPRSS3
Other Name(s): tumor-associated differentially-expressed gene 12 protein | TMPRSS3 variant F | Tumor-associated differentially-expressed gene 12 protein | Transmembrane serine protease 3, transcript variant C | TMPRSS3 variant C | TMPRSS3 variant b | Transmembrane serine protease 3, transcript variant F | TMPRSS3 variant D | Tumor associated differentially-expressed gene-12 protein | Serine protease TADG12 | ECHOS1 | DFNB8 | TMPRSS3 variant A | TMPRSS3 variant G | Transmembrane protease serine 3 (isoform 1) | Transmembrane protease serine 3 (isoform 3) | Transmembrane serine protease 3, transcript variant A | Serine protease TADG-12 | serine protease TADG-12 | TADG12 | Transmembrane protease, serine 3, transcript variant b | TMPS3_HUMAN | Transmembrane protease serine 3 (isoform 2) | DFNB10 | Transmembrane protease serine 3 | transmembrane protease, serine 3 | transmembrane serine protease 3 | Transmembrane protease, serine 3, transcript variant G | Transmembrane serine protease 3, transcript variant D | Transmembrane protease serine 3 (isoform 4)

TMPRSS3: A Potential Drug Target for Cancer

TMPRSS3 (Tumor-Associated Differentially-Expressed Gene 3) is a protein that has been identified as a potential drug target or biomarker in various diseases, including cancer. The protein is derived from the tumor-associated gene expression profile (TAGP), which identifies genes that are differentially expressed in cancer compared to normal tissue. TMPRSS3 is one of the most highly differentially expressed genes in cancer, and has been shown to be involved in various cellular processes, including cell signaling, cell adhesion, and cell survival.

TMPRSS3 is a member of the transforming growth factor receptor gene (TGFR) family, which is involved in cell signaling and growth regulation. TGF-RTK is a well-known protein that is involved in the regulation of cell growth, differentiation, and survival. TMPRSS3 is similar to TGF-RTK in terms of its sequence and structure, and is thought to function similarly in terms of its function.

TMPRSS3 is expressed in a variety of tissues and cells, including cancer cells, normal epithelial cells, and blood vessels. It has been shown to be involved in the regulation of cell proliferation, differentiation, and survival. For example, TMPRSS3 has been shown to be involved in the regulation of cell cycle progression, and has been shown to induce cell proliferation in various cell types. It has also been shown to be involved in the regulation of cell adhesion, and has been shown to play a role in the development of cancer.

TMPRSS3 has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. It has been shown to be involved in the regulation of vascular permeability, and has been shown to play a role in the development of cancer by promoting the formation of new blood vessels.

In addition to its involvement in cell signaling and angiogenesis, TMPRSS3 has also been shown to be involved in the regulation of inflammation. It has been shown to be involved in the regulation of immune cell function, and has been shown to play a role in the development of cancer by promoting the growth and survival of cancer cells.

Overall, TMPRSS3 is a protein that has been identified as a potential drug target or biomarker in a variety of diseases, including cancer. Its involvement in cell signaling, angiogenesis, and inflammation makes it a promising target for future research and development. Further studies are needed to fully understand the function of TMPRSS3 and its potential as a drug.

Protein Name: Transmembrane Serine Protease 3

Functions: Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro)

The "TMPRSS3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMPRSS3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TMPRSS4 | TMPRSS5 | TMPRSS6 | TMPRSS7 | TMPRSS9 | TMSB10 | TMSB15A | TMSB15B | TMSB4X | TMSB4XP1 | TMSB4XP2 | TMSB4XP4 | TMSB4XP8 | TMSB4Y | TMTC1 | TMTC2 | TMTC3 | TMTC4 | TMUB1 | TMUB2 | TMX1 | TMX2 | TMX2-CTNND1 | TMX3 | TMX4 | TNC | TNF | TNF receptor-associated factor (TRAF) | TNFAIP1 | TNFAIP2 | TNFAIP3 | TNFAIP6 | TNFAIP8 | TNFAIP8L1 | TNFAIP8L2 | TNFAIP8L2-SCNM1 | TNFAIP8L3 | TNFRSF10A | TNFRSF10A-DT | TNFRSF10B | TNFRSF10C | TNFRSF10D | TNFRSF11A | TNFRSF11B | TNFRSF12A | TNFRSF13B | TNFRSF13C | TNFRSF14 | TNFRSF14-AS1 | TNFRSF17 | TNFRSF18 | TNFRSF19 | TNFRSF1A | TNFRSF1B | TNFRSF21 | TNFRSF25 | TNFRSF4 | TNFRSF6B | TNFRSF8 | TNFRSF9 | TNFSF10 | TNFSF11 | TNFSF12 | TNFSF12-TNFSF13 | TNFSF13 | TNFSF13B | TNFSF14 | TNFSF15 | TNFSF18 | TNFSF4 | TNFSF8 | TNFSF9 | TNIK | TNIP1 | TNIP2 | TNIP2P1 | TNIP3 | TNK1 | TNK2 | TNK2-AS1 | TNKS | TNKS1BP1 | TNKS2 | TNMD | TNN | TNNC1 | TNNI1 | TNNI2 | TNNI3 | TNNI3K | TNNT1 | TNNT2 | TNNT3 | TNP1 | TNP2 | TNPO1 | TNPO2 | TNPO3 | TNR | TNRC17