SULT2A1: A Potential Drug Target Or Biomarker (G6822)

Target Name: SULT2A1

NCBI ID: G6822

SULT2A1

SULT2A1: A Potential Drug Target Or Biomarker

SULT2A1 (stimulated open reading mode 2A1) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, obesity, and neurodegenerative disorders. SULT2A1 is a member of the SULT gene family, which is known for producing a variety of enzymes that help regulate DNA repair and other cellular processes.

SULT2A1 has been shown to be involved in a number of cellular processes that are important for human health, including the regulation of cell growth, differentiation, and survival. It has also been linked to a number of diseases, including obesity, cancer, and neurodegenerative disorders.

One of the key features of SULT2A1 is its ability to interact with a variety of different molecules, including transcription factors, DNA repair complexes, and cellular signaling pathways. This makes it an attractive target for drugs that are designed to modulate these processes.

SULT2A1 has been shown to play a role in a number of cellular processes that are important for human health. For example, it has been shown to be involved in the regulation of cell growth and differentiation, and in the development of cancer. It has also has been linked to the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

In addition to its potential clinical applications, SULT2A1 is also of interest to researchers because of its genetic basis. The SULT gene family has been shown to be involved in a variety of cellular processes that are important for human health, including the regulation of DNA repair , metabolism, and signaling pathways. SULT2A1 is a member of this family, and its function and regulation may be important for understanding the mechanisms underlying a variety of human diseases.

Overall, SULT2A1 is a gene that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its function and potential clinical applications.

Protein Name: Sulfotransferase Family 2A Member 1

Functions: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups (PubMed:7678732, PubMed:2268288, PubMed:14573603, PubMed:18042734, PubMed:19589875, PubMed:21187059, PubMed:29671343, PubMed:7854148). Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis (PubMed:21187059, PubMed:19589875, PubMed:14573603). Plays a key role in bile acid metabolism (PubMed:2268288). In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity)

The "SULT2A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SULT2A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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