UTY: A Potential Drug Target and Biomarker for Diseases (G7404)

Target Name: UTY

NCBI ID: G7404

Content of Review Report on UTY Target / Biomarker

UTY

Other Name(s): Tetratricopeptide repeat protein | Ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome | Ubiquitously transcribed tetratricopeptide repeat gene, Y-linked | Histone demethylase UTY (isoform 23) | Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked, transcript variant 3 | UTY variant 3 | ubiquitously-transcribed TPR protein on the Y chromosome | ubiquitously transcribed tetratricopeptide repeat gene, Y-linked | Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein | Ubiquitously transcribed TPR gene on Y chromosome | [histone H3]-trimethyl-L-lysine(27) demethylase UTY | ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein | DKFZp686L12190 | UTY_HUMAN | KDM6C | Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked, transcript variant 23 | UTY1 | ubiquitous TPR motif protein UTY | UTY variant 23 | Ubiquitous TPR motif protein UTY | ubiquitously transcribed TPR gene on Y chromosome | Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein | ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome | Histone demethylase UTY (isoform 3) | KDM6AL | Ubiquitously-transcribed TPR protein on the Y chromosome | Ubiquitously transcribed TPR protein on the Y chromosome | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | OTTHUMP00000034501 | Histone demethylase UTY

UTY: A Potential Drug Target and Biomarker for Diseases

UTY (Tetratricopeptide repeat protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is made up of four amino acids that are repeated in a specific sequence, which is characteristic of this protein.

UTY is a member of a family of proteins known as the Tetratricopeptide Repeat (TPR) proteins. This family of proteins is characterized by the repeated sequence of the amino acids Phe-Asp-Glu-Asp, which is known as the TPR motif. The TPR motif is a common structural element that is found in various proteins that are involved in signaling pathways and are thought to play a role in the regulation of cellular processes such as cell growth, differentiation, and survival.

UTY is a unique protein because of its ability to form a stable binary complex with small molecules, such as drug molecules, toxins, and other substances that are capable of binding to its TPR motif. This ability makes UTY a potential drug target and a biomarker for various diseases.

One of the reasons why UTY is a promising drug target is its ability to interact with a wide range of small molecules, making it a versatile target for drug development. The TPR motif allows UTY to form stable binary complexes with small molecules that are released from various cellular organelles, including endoplasmic reticulum, cytoplasm, and mitochondria. This means that UTY can be targeted by a variety of small molecules, including drugs that are associated with various diseases, such as cancer, neurodegenerative diseases, and respiratory disorders.

In addition to its potential as a drug target, UTY is also a promising biomarker for various diseases. Its ability to form stable binary complexes with small molecules makes it a useful tool for the detection and quantification of these molecules in biological samples. For example, UTY has been used to detect and quantify drugs in various biological samples, including urine, blood, and tissue samples. This has the potential to revolutionize the field of diagnostic biomarkers, allowing for more accurate and effective disease diagnosis and treatment.

UTY is also a potential target for diseases that are characterized by the build-up of toxic substances in the body. Many diseases, including cancer, neurodegenerative diseases, and respiratory disorders, are characterized by the build-up of harmful substances, such as proteins, in the body. This build-up can lead to the formation of inclusion bodies, which can disrupt the normal functioning of cells and contribute to the development and progression of these diseases. UTY has been shown to interact with a variety of toxic substances, including drugs and environmental toxins, which suggests that it could be a useful target for diseases characterized by the build-up of toxic substances.

In conclusion, UTY is a unique protein that is characterized by its ability to form a stable binary complex with small molecules. This property makes it a potential drug target and a biomarker for various diseases. Its ability to interact with a wide range of small molecules also makes it a promising target for diagnostic biomarkers, making it an important molecule for the development of new treatments for a variety of diseases.

Protein Name: Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-linked

Functions: Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity

The "UTY Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UTY comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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