Target Name: EZR
NCBI ID: G7430
Review Report on EZR Target / Biomarker Content of Review Report on EZR Target / Biomarker
EZR
Other Name(s): Cytovillin | p81 | Villin-2 | Ezrin, transcript variant 2 | villin 2 (ezrin) | Ezrin | cytovillin 2 | EZRI_HUMAN | P81 | Epididymis secretory protein Li 105 | CVL | Cytovillin 2 | CVIL | Villin 2 (ezrin) | ezrin | VIL2 | epididymis secretory protein Li 105 | HEL-S-105 | EZR variant 2

EZR: A Natural Product with Antioxidant and Anti-Inflammatory Properties

EZR (Cytovillin) is a plant-derived natural product that has been shown to have various biological activities. One of the most promising aspects of EZR is its potential as a drug target or biomarker. In this article, we will explore the biology and potential applications of EZR.

EZR is a compound that is derived from the fruits of the cumin plant. It has been shown to have various biological activities, including anti-inflammatory, antioxidant, and anti-tumor effects. EZR has also been shown to have neuroprotective properties, which is why it is of interest as a potential therapeutic agent for neurodegenerative diseases.

One of the key biological activities of EZR is its ability to modulate the expression of genes involved in cell signaling pathways. This is accomplished through the inhibition of the protein kinase A (PKA), which is involved in a variety of cellular processes, including cell signaling, DNA replication, and cell growth. The inhibition of PKA by EZR has been shown to lead to the inhibition of the activity of several transcription factors, including NF-kappa-B, AP-1, and STAT3.

Another potential mechanism by which EZR may work is its ability to modulate the activity of the immune system. EZR has been shown to have anti-inflammatory properties, which is consistent with its potential to modulate the activity of immune cells. The ability of EZR to inhibit the production of pro-inflammatory cytokines and chemokines also supports this idea.

In addition to its potential therapeutic applications, EZR also has the potential to serve as a biomarker for several diseases. For example, EZR has been shown to have potential as a diagnostic agent for cancer, due to its ability to selectively target and label cancer cells, while avoiding the non-cancerous cells. This makes it a promising marker for cancer detection and treatment.

EZR has also been shown to have potential as a therapeutic agent for several other diseases. For example, EZR has been shown to have anti-inflammatory properties that could make it a potential therapeutic agent for the treatment of neuroinflammatory diseases, such as multiple sclerosis and rheumatoid arthritis.

In addition to its potential therapeutic and biomarker applications, EZR also has several other biological activities that are of interest. For example, EZR has been shown to have antioxidant properties, which could make it a potential therapeutic agent for the prevention of oxidative stress-induced diseases. EZR has also been shown to have anti-cancer properties, which could make it a potential therapeutic agent for cancer treatment.

In conclusion, EZR is a plant-derived natural product with a wide range of potential biological activities. Its ability to modulate the expression of genes involved in cell signaling pathways, modulate the activity of the immune system, and serve as a potential therapeutic and biomarker make it of interest as a potential therapeutic agent for a variety of diseases. Further research is needed to fully understand the biology and potential applications of EZR.

Protein Name: Ezrin

Functions: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis

The "EZR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EZR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

F10 | F11 | F11-AS1 | F11R | F12 | F13A1 | F13B | F2 | F2R | F2RL1 | F2RL2 | F2RL3 | F3 | F5 | F7 | F8 | F8A1 | F8A2 | F8A3 | F9 | FA2H | FAAH | FAAH2 | FAAHP1 | FAAP100 | FAAP20 | FAAP24 | FABP1 | FABP12 | FABP2 | FABP3 | FABP4 | FABP5 | FABP5P1 | FABP5P10 | FABP5P11 | FABP5P2 | FABP5P3 | FABP5P7 | FABP6 | FABP7 | FABP7P1 | FABP9 | FACT complex | FADD | FADS1 | FADS2 | FADS2B | FADS3 | FADS6 | FAF1 | FAF2 | FAH | FAHD1 | FAHD2A | FAHD2B | FAHD2CP | FAIM | FAIM2 | FALEC | FAM104A | FAM104B | FAM106A | FAM106C | FAM107A | FAM107B | FAM110A | FAM110B | FAM110C | FAM110D | FAM111A | FAM111A-DT | FAM111B | FAM114A1 | FAM114A2 | FAM117A | FAM117B | FAM118A | FAM118B | FAM120A | FAM120A2P | FAM120AOS | FAM120B | FAM120C | FAM124A | FAM124B | FAM131A | FAM131B | FAM131B-AS2 | FAM131C | FAM133A | FAM133B | FAM133CP | FAM133DP | FAM135A | FAM135B | FAM136A | FAM136BP | FAM138A | FAM138B