Target Name: KLHL5
NCBI ID: G51088
Review Report on KLHL5 Target / Biomarker Content of Review Report on KLHL5 Target / Biomarker
KLHL5
Other Name(s): KLHL5a | FLJ11313 | KLHL5 variant 1 | Lymphocyte activation-associated protein | kelch like family member 5 | DKFZp586M1418 | OTTHUMP00000218210 | OTTHUMP00000218211 | OTTHUMP00000123483 | lymphocyte activation-associated protein | OTTHUMP00000123484 | Kelch-like protein 5 | KLHL5_HUMAN | Kelch-like 5 (Drosophila), transcript variant 1 | Kelch-like protein 5 (isoform 1) | OTTHUMP00000123482

KLHL5a: A Promising Drug Target and Biomarker

The KLHL5 (KLHL5a) gene is a non-coding RNA molecule that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of stem cell proliferation and has been implicated in the development and progression of several diseases, including cancer.

Recent studies have identified KLHL5a as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these conditions has been studied extensively, and its potential as a drug has been evaluated in preclinical and clinical trials.

One of the key advantages of KLHL5a as a drug target is its expression in a variety of tissues, which makes it less likely to cause off-target effects. This makes it a more reliable and safer drug target than some other genes, such as the T-cell receptor alpha chain (TCR伪), which is expressed in many different tissues and is more prone to unintended consequences.

In addition to its potential as a drug target, KLHL5a has also been identified as a potential biomarker for several diseases. Its expression has been shown to be downregulated in a variety of cancer types, and it has been used as a biomarker for cancer diagnosis and treatment.

One of the main challenges in studying KLHL5a as a drug target is its complex function in the body. It is expressed in many different tissues and is involved in a wide range of biological processes, making it difficult to understand exactly how it contributes to the development and progression of disease.

However, recent studies have provided some insight into the function of KLHL5a in various tissues and conditions. For example, researchers have shown that KLHL5a is involved in the regulation of stem cell proliferation and that it can induce stem cells to differentiate into functional brain cells.

In addition, studies have also shown that KLHL5a is involved in the regulation of immune cells, including T cells. This makes it a potential target for drugs that aim to improve immune function and protect against infection.

The potential clinical applications of KLHL5a as a drug target and biomarker are vast and varied. In addition to its potential uses in cancer and neurodegenerative diseases, KLHL5a has also been shown to be involved in the regulation of inflammation and immune function, making it a potential target for drugs that aim to improve these functions.

As with any new drug target, the development and testing of KLHL5a as a drug will require careful consideration and oversight. Researchers will need to conduct extensive studies to fully understand its function and potential as a drug, and to determine its safety and effectiveness in clinical trials.

Overall, KLHL5a is a promising gene as a potential drug target and biomarker for a variety of diseases. Its complex function in various tissues and conditions makes it a more reliable and safer option than some other genes, and its potential as a drug and biomarker is expected to continue to be explored in the years to come.

Protein Name: Kelch Like Family Member 5

The "KLHL5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLHL5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KLHL6 | KLHL7 | KLHL7-DT | KLHL8 | KLHL9 | KLK1 | KLK10 | KLK11 | KLK12 | KLK13 | KLK14 | KLK15 | KLK2 | KLK3 | KLK4 | KLK5 | KLK6 | KLK7 | KLK8 | KLK9 | KLKB1 | KLKP1 | KLLN | KLRA1P | KLRB1 | KLRC1 | KLRC2 | KLRC3 | KLRC4 | KLRC4-KLRK1 | KLRD1 | KLRF1 | KLRF2 | KLRG1 | KLRG2 | KLRK1 | KLRK1-AS1 | KMO | KMT2A | KMT2B | KMT2C | KMT2CP4 | KMT2D | KMT2E | KMT2E-AS1 | KMT5A | KMT5B | KMT5C | KNCN | KNDC1 | KNG1 | KNL1 | KNOP1 | KNOP1P5 | KNSTRN | KNTC1 | KPNA1 | KPNA2 | KPNA3 | KPNA4 | KPNA5 | KPNA6 | KPNA7 | KPNB1 | KPNB1-DT | KPRP | KPTN | KRAS | KRASP1 | KRBA1 | KRBA2 | KRBOX1 | KRBOX1-AS1 | KRBOX4 | KRBOX5 | KRCC1 | KREMEN1 | KREMEN2 | KRI1 | KRIT1 | KRR1 | KRT1 | KRT10 | KRT10-AS1 | KRT12 | KRT126P | KRT13 | KRT14 | KRT15 | KRT16 | KRT16P1 | KRT16P2 | KRT16P3 | KRT16P6 | KRT17 | KRT17P1 | KRT17P2 | KRT17P3 | KRT17P5 | KRT17P7