KLHL7: A Potential Drug Target and Biomarker (G55975)

Target Name: KLHL7

NCBI ID: G55975

KLHL7

KLHL7: A Potential Drug Target and Biomarker

KLHL7, also known as Kelch-like 7, is a protein that is expressed in various tissues and cells throughout the body. It is a member of the Kelch family of proteins, which are involved in the regulation of cell signaling pathways. KLHL7 has been identified as a potential drug target and biomarker due to its unique structure and function.

The Kelch family of proteins was named after Dr. William Kelch, a renowned biochemist who first identified the protein in the 1960s. The protein is characterized by a unique arrangement of multiple domains, including a catalytic domain, a nucleotide-binding domain, and a carboxy-terminal domain. The catalytic domain is responsible for the protein's catalytic activity, while the nucleotide-binding domain interacts with nucleotides in the cell signaling pathway. The carboxy-terminal domain is involved in the regulation of the protein's stability and localization.

KLHL7 is a 21-kDa protein that is expressed in various tissues and cells, including brain, heart, skeletal muscles, and tissues. It is involved in the regulation of several cellular processes, including cell signaling pathways, DNA replication, and cell adhesion. KLHL7 has been shown to play a role in the regulation of neurotransmitter release from nerve axons, which is critical for the function of the brain.

As a potential drug target, KLHL7 is attractive due to its unique structure and function. The protein is involved in multiple cellular processes that are crucial for normal cellular function, making it an attractive target for small molecules that can modulate these processes. Additionally, KLHL7 is a protein that is expressed in various tissues, which makes it an attractive target for drugs that can affect protein levels in different tissues.

In addition to its potential as a drug target, KLHL7 has also been identified as a biomarker for several diseases. For example, KLHL7 has been shown to be involved in the regulation of the production of cancer cells. In addition, the protein has been shown to be involved in the regulation of inflammation, which is a critical aspect of many diseases.

In conclusion, KLHL7 is a protein that has unique structure and function, making it an attractive target for small molecules. Its involvement in the regulation of multiple cellular processes makes it an attractive target for drugs that can modulate these processes. Additionally, KLHL7 has been identified as a biomarker for several diseases, which makes it an attractive target for drugs that can affect protein levels in different tissues. Further research is needed to fully understand the role of KLHL7 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Kelch Like Family Member 7

Functions: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination

The "KLHL7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLHL7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets