KLHL35: A Potential Drug Target and Biomarker (G283212)

Target Name: KLHL35

NCBI ID: G283212

KLHL35

KLHL35: A Potential Drug Target and Biomarker

KLHL35, also known as Kelch-like 35, is a protein that is expressed in various tissues, including the brain, heart, and lungs. Its function and specificity are still under investigation, but research has shown that it plays a significant role in various physiological processes. As a result, KLHL35 has gained interest as a potential drug target and biomarker.

The discovery of KLHL35

KLHL35 was first identified as a protein that is expressed in the brain and is characterized by its presence in the ventricular region of the brain. Studies have shown that KLHL35 is expressed in the hippocampus, a region of the brain that is responsible for memory and learning. Additionally, KLHL35 has been observed in the other brain regions, including the prefrontal cortex, cerebellum, and spinal cord.

The unique feature of KLHL35 is its structure, which is similar to that of the protein kelch, which is known for its role in cell signaling. Kelch is a type of protein that is characterized by its ability to interact with G protein-coupled receptors (GPCRs). KLHL35 is thought to have similar properties and is potential drug target.

KLHL35's role in cell signaling

KLHL35 has been shown to play a role in cell signaling in various tissues. For example, studies have shown that KLHL35 can interact with the protein PyR, which is involved in cell signaling. Additionally, KLHL35 has been shown to interact with the protein Fyn, which is involved in the regulation of cell signaling.

KLHL35's potential as a drug target

KLHL35's role in cell signaling makes it a potential drug target. Its interactions with various proteins suggest that it may be involved in various signaling pathways, including those related to pain, inflammation, and stress. Additionally, KLHL35's expression in various tissues, including the brain, makes it a potential biomarker for certain diseases.

KLHL35's potential as a biomarker

KLHL35's expression in various tissues makes it a potential biomarker for various diseases. For example, KLHL35 has been shown to be expressed in the brains of individuals with Alzheimer's disease, a condition that is characterized by the progressive loss of brain cells. Additionally, KLHL35 has been shown to be expressed in the hearts of individuals with heart failure, a condition that is characterized by the progressive loss of heart muscle.

Conclusion

In conclusion, KLHL35 is a protein that has been identified as potentially playing a role in various physiological processes. Its unique structure and interactions with various proteins make it a potential drug target. Additionally, its expression in various tissues makes it a potential biomarker for various diseases. Further research is needed to fully understand the role of KLHL35 in cell signaling and its potential as a drug target and biomarker.

Protein Name: Kelch Like Family Member 35

The "KLHL35 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLHL35 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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