UTP15: A Potential Drug Target and Biomarker (G84135)

Target Name: UTP15

NCBI ID: G84135

UTP15

UTP15: A Potential Drug Target and Biomarker

UTP15, also known as src-associated protein SAW, is a protein that is expressed in various tissues, including the brain, heart, and liver. Its primary function is to regulate the actinin filament, which is a protein that forms the cytoskeleton and plays a crucial role in cell movement and mechanical forces. UTP15 has also been shown to be involved in a variety of cellular processes, including cell signaling, DNA replication, and repair.

Recent studies have identified UTP15 as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is due to UTP15's involvement in various cellular processes that are disrupted in these conditions, as well as its unique expression patterns in different tissues.

One of the key reasons for the potential of UTP15 as a drug target is its involvement in cell signaling. UTP15 has been shown to play a role in regulating the actinin filament, which is a protein that forms the cytoskeleton and acts as a scaffold to keep cells in a specific shape. In addition, UTP15 has been shown to interact with various signaling molecules, including TP53, P21, and NF-kappa-B. These interactions suggest that UTP15 may be a target for drugs that can inhibit these signaling pathways.

Another potential drug target for UTP15 is its role in DNA replication and repair. UTP15 has been shown to be involved in the regulation of DNA replication, as well as in the repair of DNA damage. This suggests that UTP15 may be a target for drugs that can inhibit these processes, which could be useful for treating a variety of diseases, including cancer.

In addition to its potential as a drug target, UTP15 has also been identified as a potential biomarker for a variety of diseases. This is due to its expression patterns, which are often altered in diseases such as cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that UTP15 levels are often elevated in various tissues, including the brain, heart, and liver, which suggests that it may be a useful biomarker for these conditions.

Another potential application of UTP15 as a biomarker is its role in cell migration. UTP15 has been shown to play a role in regulating cell migration, which is a critical process for the development and progression of many diseases. In addition, UTP15 has been shown to interact with the protein vimentin, which is also involved in cell migration. This suggests that UTP15 may be a target for drugs that can inhibit cell migration, which could be useful for treating a variety of diseases.

In conclusion, UTP15 is a protein that has been shown to be involved in a variety of cellular processes, including cell signaling, DNA replication, and repair, as well as cell migration. Its unique expression patterns and involvement in these processes make it a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of UTP15 in these processes and to develop effective treatments.

Protein Name: UTP15 Small Subunit Processome Component

Functions: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

The "UTP15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UTP15 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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