MKNK1 Plays A Crucial Role in Cell Apoptosis, Cycle Progression, Angiogenesis and Signaling
MKNK1 Plays A Crucial Role in Cell Apoptosis, Cycle Progression, Angiogenesis and Signaling
MKNK1, also known as MKNK1-HUMAN, is a protein that is expressed in a variety of tissues throughout the body. It is a part of the superfamily of metal-binding proteins, which include enzymes that play a critical role in the regulation of cellular processes such as metabolism, DNA replication, and cell signaling.
MKNK1 is highly conserved across various species, and its structure is similar to that of other members of its superfamily. It consists of a unique N-terminal domain that contains a conserved nucleotide-binding oligomerization domain (NBO), which is responsible for the protein's metal-binding properties. The NBO domain is composed of a nucleotide-binding oligomerization motif (NBM) and a 尾-sheet that are involved in the formation of a distinct 3D structure.
MKNK1 is known to play a critical role in the regulation of cellular processes that are involved in the development and progression of various diseases, including cancer. It is involved in the regulation of cell cycle progression, apoptosis, and angiogenesis, which are processes that are critical for the growth and development of cancer cells.
One of the most significant functions of MKNK1 is its role in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death. During apoptosis, MKNK1 is involved in the formation of a stress-associated protein network (SAP), which is a complex of proteins that are involved in the regulation of cellular processes that are critical for stress responses.
MKNK1 is also involved in the regulation of cell cycle progression, and is known to play a critical role in the G1 phase of the cell cycle. During the G1 phase, MKNK1 is involved in the accumulation of mobile genetic elements (MGEs) in the cytoplasm , which are then transported to the center of the cell during the G2 phase. This process is important for the delivery of genetic material to the center of the cell and for the proper execution of cellular processes.
In addition to its role in cell apoptosis and cell cycle progression, MKNK1 is also involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. It is known to play a critical role in the regulation of angiogenesis by promoting the migration of endothelial cells to new blood vessels.
MKNK1 is also involved in the regulation of cellular signaling, and is known to play a critical role in the regulation of T cell responses. It is involved in the regulation of the development and function of T cells, and is known to play a critical role in the regulation of T cell receptor (TCR) signaling.
MKNK1 is also involved in the regulation of inflammation, and is known to play a critical role in the regulation of inflammatory responses. It is involved in the regulation of the production and function of pro-inflammatory cytokines, and is known to play a critical role in the regulation of the immune response.
MKNK1 is a protein that is expressed in a variety of tissues throughout the body, and is involved in the regulation of cellular processes that are critical for the growth and development of cancer cells. It is a potential drug target and biomarker for a variety of diseases , including cancer. Further research is needed to fully understand the functions of MKNK1 and its potential as a drug target.
Protein Name: MAPK Interacting Serine/threonine Kinase 1
Functions: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap
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More Common Targets
MKNK1-AS1 | MKNK2 | MKRN1 | MKRN2 | MKRN2OS | MKRN3 | MKRN4P | MKRN7P | MKRN9P | MKS1 | MKX | MLANA | MLC1 | MLEC | MLF1 | MLF1-DT | MLF2 | MLH1 | MLH3 | MLIP | MLIP-AS1 | MLKL | MLLT1 | MLLT10 | MLLT10P1 | MLLT11 | MLLT3 | MLLT6 | MLN | MLNR | MLPH | MLST8 | MLX | MLXIP | MLXIPL | MLYCD | MMAA | MMAB | MMACHC | MMADHC | MMADHC-DT | MMD | MMD2 | MME | MMEL1 | MMGT1 | MMP | MMP1 | MMP10 | MMP11 | MMP12 | MMP13 | MMP14 | MMP15 | MMP16 | MMP17 | MMP19 | MMP2 | MMP2-AS1 | MMP20 | MMP20-AS1 | MMP21 | MMP23A | MMP23B | MMP24 | MMP24-AS1-EDEM2 | MMP24OS | MMP25 | MMP25-AS1 | MMP26 | MMP27 | MMP28 | MMP3 | MMP7 | MMP8 | MMP9 | MMRN1 | MMRN2 | MMS19 | MMS22L | MMS22L-TONSL complex | MMUT | MMXD complex | MN1 | MNAT1 | MND1 | MNDA | MNS1 | MNT | MNX1 | MNX1-AS1 | MOAP1 | MOB1A | MOB1B | MOB2 | MOB3A | MOB3B | MOB3C | MOB4 | MOBP
