Target Name: NUDT13
NCBI ID: G25961
Review Report on NUDT13 Target / Biomarker Content of Review Report on NUDT13 Target / Biomarker
NUDT13
Other Name(s): NUDT13 variant 1 | NAD(P)H pyrophosphatase NUDT13, mitochondrial | nucleoside diphosphate-linked moiety X motif 13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 | nudix motif 13 | NAD(P)H pyrophosphatase NUDT13, mitochondrial (isoform a) | NUD13_HUMAN | Protein KiSS-16 | nudix hydrolase 13 | Nudix hydrolase 13, transcript variant 1 | Nudix motif 13

Studies Show NUDT13 as Potential Drug Target for Neurological Disorders

NUDT13, also known as NUDT13 variant 1, is a protein that is expressed in various tissues throughout the body, including the brain, muscle, and heart. It is a member of the NUDT family of proteins, which are known for their role in regulating neurotransmitter signaling.

Recent studies have identified NUDT13 as a potential drug target or biomarker for various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. This is because NUDT13 has been shown to play a role in the transmission of signals in these conditions, and in modulating the activity of neurotransmitters such as dopamine and serotonin.

One of the key reasons for the potential utility of NUDT13 as a drug target is its involvement in the regulation of neurotransmitter signaling. NUDT13 has been shown to play a role in the modulation of dopamine release from brain neurons, and to regulate the activity of dopamine transporter in brain cells. This suggests that NUDT13 may be a useful target for interventions aimed at modulating dopamine levels in the brain.

In addition to its role in neurotransmission, NUDT13 has also been shown to be involved in the regulation of cellular signaling processes. For example, NUDT13 has been shown to play a role in the regulation of cell adhesion, as well as in the regulation of cell cycle progression.

Given its involvement in a wide range of cellular processes, NUDT13 has potential as a drug target or biomarker for a wide range of neurological and psychiatric disorders. Studies are currently being conducted to determine the exact mechanisms by which NUDT13 is involved in these conditions, as well as to identify potential small molecules or other compounds that can modulate its activity.

While the potential utility of NUDT13 as a drug target or biomarker is still being explored, it is clear that NUDT13 is an important protein that is involved in a wide range of cellular processes. Further research is needed to fully understand its role in neurological and psychiatric disorders, and to identify potential therapeutic compounds.

Protein Name: Nudix Hydrolase 13

Functions: NAD(P)H pyrophosphatase that hydrolyzes NADH into NMNH and AMP, and NADPH into NMNH and 2',5'-ADP. Has a marked preference for the reduced pyridine nucleotides. Does not show activity toward NAD-capped RNAs; the NAD-cap is an atypical cap present at the 5'-end of some RNAs

The "NUDT13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUDT13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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NUDT14 | NUDT15 | NUDT15P1 | NUDT16 | NUDT16-DT | NUDT16L1 | NUDT16L2P | NUDT17 | NUDT18 | NUDT19 | NUDT2 | NUDT21 | NUDT22 | NUDT3 | NUDT4 | NUDT4B | NUDT4P2 | NUDT5 | NUDT6 | NUDT7 | NUDT8 | NUDT9 | NUDT9P1 | NUF2 | NUFIP1 | NUFIP2 | NUGGC | NUMA1 | NUMB | NUMBL | NUP107 | Nup107-160 complex | NUP133 | NUP153 | NUP155 | NUP160 | NUP188 | NUP205 | NUP210 | NUP210L | NUP210P1 | NUP210P2 | NUP214 | NUP35 | NUP37 | NUP42 | NUP43 | NUP50 | NUP50-DT | NUP54 | NUP58 | NUP62 | NUP62CL | NUP85 | NUP88 | NUP93 | NUP98 | NUPR1 | NUPR2 | NUS1 | NUS1P1 | NUS1P3 | NUSAP1 | NUTF2 | NUTF2P4 | NUTM1 | NUTM2A | NUTM2A-AS1 | NUTM2B | NUTM2B-AS1 | NUTM2D | NUTM2E | NUTM2F | NUTM2G | NVL | NWD1 | NWD2 | NXF1 | NXF2 | NXF3 | NXF4 | NXF5 | NXN | NXNL1 | NXNL2 | NXPE1 | NXPE2 | NXPE3 | NXPE4 | NXPH1 | NXPH2 | NXPH3 | NXPH4 | NXT1 | NXT2 | NXTAR | NYAP1 | NYAP2 | NYNRIN | NYX