Target Name: ZNF443
NCBI ID: G10224
Review Report on ZNF443 Target / Biomarker Content of Review Report on ZNF443 Target / Biomarker
ZNF443
Other Name(s): Zinc finger protein 443 | Krueppel-type zinc finger protein ZK1 | Kruppel-type zinc finger (C2H2) | OTTHUMP00000209833 | krueppel-type zinc finger protein ZK1 | zinc finger protein 443 | ZK1 | ZN443_HUMAN

ZNF443: A Potential Drug Target and Biomarker for Neurodegenerative Disorders

Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, are progressive conditions that affect the brain and cause progressive cognitive decline and motor dysfunction. These conditions are characterized by the progressive loss of brain cells, leading to a decline in cognitive function and an increase in the risk of disability.

One of the underlying causes of neurodegenerative diseases is the misfolding of proteins, which results in the formation of aggregates that are toxic to nerve cells and the formation of neurofibrillary tangles, which are also toxic to nerve cells. ZNF443, a gene that encodes a zinc finger protein, has been identified as a potential drug target and biomarker for neurodegenerative disorders.

The ZNF443 Gene and its Expression

ZNF443 is a gene that encodes a zinc finger protein that plays a role in the regulation of neural development and survival. The zinc finger gene is a family of transmembrane proteins that are characterized by the presence of a zinc finger domain at their extracellular domain. The zinc finger domain is a structural element that is involved in the formation of aggregates and is thought to play a role in the regulation of protein stability and localization.

ZNF443 has been shown to be expressed in a variety of tissues and cells, including brain, spinal cord, and muscle. It has also been shown to be involved in the regulation of neural development and survival, and is thought to play a role in the development and progression of neurodegenerative diseases.

The Potential Role of ZNF443 as a Drug Target

The misfolding of proteins is a key event in the development of neurodegenerative diseases, and the formation of aggregates and neurofibrillary tangles is thought to be a hallmark of these conditions. ZNF443 has been shown to be involved in the regulation of protein stability and localization, and is thought to play a role in the regulation of neural development and survival.

Given these findings, ZNF443 is a potential drug target for neurodegenerative diseases. Drugs that target ZNF443 have the potential to disrupt the formation of aggregates and neurofibrillary tangles, which could potentially slow the progression of neurodegenerative diseases.

The Potential Role of ZNF443 as a Biomarker

In addition to its potential as a drug target, ZNF443 is also a potential biomarker for neurodegenerative diseases. The misfolding of proteins is a key event in the development of neurodegenerative diseases, and the formation of aggregates and neurofibrillary tangles is thought to be a hallmark of these conditions.

ZNF443 has been shown to be involved in the regulation of protein stability and localization, and is thought to play a role in the regulation of neural development and survival. Given these findings, ZNF443 has the potential to serve as a biomarker for neurodegenerative diseases, and may be used as a diagnostic tool for these conditions.

Conclusion

ZNF443 is a gene that encodes a zinc finger protein that has been identified as a potential drug target and biomarker for neurodegenerative diseases. The misfolding of proteins is a key event in the development of these conditions, and the formation of aggregates and neurofibrillary tangles is thought to be a hallmark of these conditions. ZNF443 has the potential to disrupt the formation of these aggregates and tangles, making it a promising target for drugs that

Protein Name: Zinc Finger Protein 443

Functions: May be involved in transcriptional regulation

The "ZNF443 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF443 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568 | ZNF569 | ZNF56P | ZNF57