SLC46A3: A Potential Drug Target and Biomarker for Diseases (G283537)

Target Name: SLC46A3

NCBI ID: G283537

SLC46A3

SLC46A3: A Potential Drug Target and Biomarker for Diseases

SLC46A3, also known as isoform b, is a member of the Absolute Carrier Family 46 (ABC). This family of proteins plays a crucial role in the transport of various molecules across cell membranes, including small molecules, ions, and drugs. SLC46A3 is a widely expressed protein that is found in many different cell types, including muscle, nerve, and heart cells.

One of the key functions of SLC46A3 is its role as a drug transport protein. It is expressed in high levels in the liver and other organs and is involved in the transport of a wide variety of drugs, including many proteins, nucleic acids, and metabolites. This protein is also expressed in the placenta, which is responsible for transporting fetal proteins and hormones across the mother's blood-brain barrier.

In addition to its role in drug transport, SLC46A3 is also a potential biomarker for several diseases. For example, it has been shown to be highly expressed in the brains of individuals with Alzheimer's disease, and high levels of this protein have also been detected in the urine and plasma of individuals with Parkinson's disease.

SLC46A3 is also expressed in various tissues and organs and has been shown to play a role in several physiological processes, including cell signaling, neurotransmission, and hormone regulation. For example, SLC46A3 has been shown to be involved in the regulation of pain signaling, and it has also been shown to play a role in the regulation of appetite and metabolism.

Furthermore, SLC46A3 has also been shown to be a potential target for new drugs. Many drugs that are currently being developed for the treatment of various diseases, including Alzheimer's disease and Parkinson's disease, are designed to block the function of SLC46A3. This is because SLC46A3 is thought to be involved in the transport of drugs across cell membranes, and blocking its function could potentially lead to a more effective treatment of these diseases.

In conclusion, SLC46A3 is a widely expressed and important protein that plays a crucial role in the transport of drugs across cell membranes. Its potential as a drug target and its involvement in various physiological processes make it an attractive target for new therapies. Further research is needed to fully understand the role of SLC46A3 in disease and to develop new treatments based on its unique properties.

Protein Name: Solute Carrier Family 46 Member 3

The "SLC46A3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC46A3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets