SLC49A3: A Potential Drug Target for Ion Transport and Signaling

Target Name: SLC49A3

NCBI ID: G84179

SLC49A3

SLC49A3: A Potential Drug Target for Ion Transport and Signaling

SLC49A3, also known as SLC49A3 gene, is a member of the Solute carrier family 49 that is located on chromosome 12. It is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. The function of SLC49A3 is not yet fully understood, but it is believed to play a role in the regulation of ion transport and signaling in these tissues.

SLC49A3 is a transmembrane protein, which means that it spans the entire thickness of the membrane and is involved in the regulation of the movement of ions and molecules across the membrane. It is made up of four structural domains: an N-terminus, a transmembrane domain, a C-terminus, and an additional N-terminus that is located within the cytoplasm. The transmembrane domain is responsible for the regulation of the activity of the protein and is the region where most of the protein's function is located.

One of the unique features of SLC49A3 is its structure. It has a unique arrangement of hydrophobic and hydrophilic regions, which allows it to have both a hydrophobic and hydrophilic orientation. This is important for the protein's ability to interact with both water-soluble and hydrophobic molecules.

SLC49A3 is also known for its role in the regulation of ion transport. It is a member of the Sodium Chloride Transporter (SCT) family, which is responsible for regulating the movement of sodium and chloride ions across the membrane of various tissues. This is important for maintaining the proper levels of these ions in the body and is involved in a wide range of physiological processes, including muscle contractions, nerve function, and blood pressure.

In addition to its role in ion transport, SLC49A3 is also thought to be involved in the regulation of signaling pathways. It is a component of several signaling pathways that are involved in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

SLC49A3 is also of interest as a potential drug target. Its unique structure and its involvement in several important cellular processes make it a potential target for small molecules. Studies have shown that SLC49A3 is responsive to small molecules such as inhibitors, regulators, and modulators.

In conclusion, SLC49A3 is a protein that is expressed in various tissues of the body and is involved in the regulation of ion transport and signaling pathways. Its unique structure and its involvement in several important cellular processes make it a potential target for small molecules. Further research is needed to fully understand the function of SLC49A3 and its potential as a drug.

Protein Name: Solute Carrier Family 49 Member 3

The "SLC49A3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC49A3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets