Target Name: ALDH1L1
NCBI ID: G10840
Review Report on ALDH1L1 Target / Biomarker Content of Review Report on ALDH1L1 Target / Biomarker
ALDH1L1
Other Name(s): 10-fTHF | Aldehyde dehydrogenase 1 family member L1, transcript variant 2 | aldehyde dehydrogenase 1 family member L1 | Aldehyde dehydrogenase 1 family member L1, transcript variant 1 | DKFZp781N0997 | ALDH1L1 variant 2 | Cytosolic 10-formyltetrahydrofolate dehydrogenase (isoform 1) | 10-FTHFDH | Cytosolic 10-formyltetrahydrofolate dehydrogenase | AL1L1_HUMAN | ALDH1L1 variant 1 | FTHFD | Aldehyde dehydrogenase family 1 member L1 | Cytosolic 10-formyltetrahydrofolate dehydrogenase (isoform 2) | 10-formyltetrahydrofolate dehydrogenase | FDH | MER57B-ALDH1L1 | Formyltetrahydrofolate dehydrogenase

ALDH1L1: A Protein Involved in Cell Survival and Function

ALDH1L1 (10-fTHF) is a protein that is expressed in a variety of tissues throughout the body, including the liver, heart, lungs, and kidneys. It is a member of the alkaline phosphatase gene family (APG) and is involved in a variety of physiological processes that are important for cell survival and function.

One of the functions of ALDH1L1 is its role in the regulation of cellular homeostasis. ALDH1L1 is a key enzyme in the tricarboxylic acid (TCA) cycle, which is a central metabolic pathway that is involved in the production of energy from the food we eat. During the TCA cycle, ALDH1L1 helps to maintain the proper balance of acids in the cell, which is critical for maintaining the stability and integrity of various cellular structures and processes.

Another function of ALDH1L1 is its role in the regulation of cellular signaling. ALDH1L1 is involved in a variety of signaling pathways that are important for the development and maintenance of tissues and organs. For example, ALDH1L1 is involved in the regulation of cell adhesion, which is critical for the development and maintenance of tissues and organs, and ALDH1L1 is also involved in the regulation of cell proliferation, which is important for the growth and development of tissues and organs.

In addition to its role in cellular homeostasis and signaling, ALDH1L1 is also involved in the regulation of cellular waste removal. ALDH1L1 is involved in the production of extracellular matrix (ECM) components, which are important for the support and structure of tissues and organs. ECM components are constantly being removed from the body and ALDH1L1 is involved in the production of the enzymes that are responsible for this process.

Despite its involvement in a variety of important cellular processes, ALDH1L1 is not well understood. There are currently very few studies that have been conducted to determine the specific functions of ALDH1L1, and much of the research that has been done on this protein has been focused on its potential as a drug target.

One potential mechanism by which ALDH1L1 could be targeted as a drug is its role in the regulation of cellular signaling. Many drugs that are used to treat a variety of diseases, such as cancer, have been shown to disrupt the signaling pathways that are involved in the regulation of cellular homeostasis and growth. By disrupting the signaling pathways that are involved in the regulation of ALDH1L1, drugs could potentially be used to treat a variety of diseases.

Another potential mechanism by which ALDH1L1 could be targeted as a drug is its role in the regulation of cellular waste removal. Many drugs that are used to treat a variety of diseases, such as diabetes, have been shown to disrupt the processes that are involved in the regulation of cellular waste removal. By disrupting the processes that are involved in the regulation of ALDH1L1, drugs could potentially be used to treat a variety of diseases.

In conclusion, ALDH1L1 is a protein that is involved in a variety of important cellular processes that are critical for the survival and function of tissues and organs. Despite its involvement in these processes, ALDH1L1 is not well understood, and there are currently few studies that have been conducted to determine its specific functions. However, its potential as a drug target due to its involvement in the regulation of cellular homeostasis and signaling, as well as its role in the regulation of cellular waste removal, make it an attractive target for future research.

Protein Name: Aldehyde Dehydrogenase 1 Family Member L1

Functions: Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436). May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde (By similarity)

The "ALDH1L1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ALDH1L1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ALDH1L1-AS1 | ALDH1L2 | ALDH2 | ALDH3A1 | ALDH3A2 | ALDH3B1 | ALDH3B2 | ALDH4A1 | ALDH5A1 | ALDH6A1 | ALDH7A1 | ALDH8A1 | ALDH9A1 | Aldo-Keto Reductase Family 1 | ALDOA | ALDOAP2 | ALDOB | ALDOC | ALG1 | ALG10 | ALG10B | ALG11 | ALG12 | ALG13 | ALG14 | ALG1L10P | ALG1L13P | ALG1L1P | ALG1L2 | ALG1L5P | ALG1L7P | ALG1L8P | ALG2 | ALG3 | ALG5 | ALG6 | ALG8 | ALG9 | ALK | ALKAL1 | ALKAL2 | Alkaline Phosphatase (ALP) | ALKBH1 | ALKBH2 | ALKBH3 | ALKBH4 | ALKBH5 | ALKBH6 | ALKBH7 | ALKBH8 | ALLC | ALMS1 | ALMS1-IT1 | ALMS1P1 | ALOX12 | ALOX12-AS1 | ALOX12B | ALOX12P2 | ALOX15 | ALOX15B | ALOX15P1 | ALOX15P2 | ALOX5 | ALOX5AP | ALOXE3 | ALPG | Alpha-2 Adrenergic receptors | alpha-6 beta-2 Nicotinic receptor | alpha-Adrenoceptor | alpha-Amylase | alpha-beta T Cell Receptor Complex (TCR) | Alpha-crystallin | alpha-Mannosidase | alpha-Secretase | alpha1-Adrenoceptor | ALPI | ALPK1 | ALPK2 | ALPK3 | ALPL | ALPP | ALS2 | ALS2CL | ALX1 | ALX3 | ALX4 | ALYREF | AMACR | AMBN | AMBP | AMBRA1 | AMD1 | AMD1P2 | AMDHD1 | AMDHD2 | AMELX | AMELY | AMER1 | AMER2 | AMER3