JTB Gene: Potential Drug Targets for Prostate Cancer (G10899)

Target Name: JTB

NCBI ID: G10899

Content of Review Report on JTB Target / Biomarker

JTB

JTB Gene: Potential Drug Targets for Prostate Cancer

Jurkat-Tunneling ankang gene (JTB, Prostate androgen-regulated) is the most common gene in rat prostate cancer. The protein encoded by this gene is a transcription factor found to play an important role in a variety of cancers. Like many cancers, the incidence and mortality of prostate cancer increase significantly in older men, and the expression levels of the JTB gene are related to age and sex. In recent years, researchers have conducted in-depth studies on the function of the JTB gene and discovered its potential in treating prostate cancer and as a drug target.

The role of JTB gene

The JTB gene is one of the genes with the highest expression in rat prostate cancer cells. The expression levels of JTB genes vary significantly in different types of prostate cancer cells. Under normal circumstances, the expression level of the JTB gene increases with age, but in prostate cancer cells, the expression level of the JTB gene increased significantly.

JTB gene transcript

The JTB gene produces multiple transcripts, the most important of which is JTB1. JTB1 is the main transcript of the JTB gene in rat prostate cancer cells, accounting for 80% of the total transcripts. The protein encoded by JTB1 is a transcription factor that has been found to play an important role in a variety of cancers.

Function of JTB gene

The function of the JTB gene is closely related to the incidence and mortality of prostate cancer. Studies have shown that the expression level of the JTB gene increases with age and is significantly increased in prostate cancer cells. These findings suggest that the JTB gene may be associated with prostate cancer progression and invasiveness.

Drug targets of JTB genes

Research on drug targets of the JTB gene is a hot topic in the field of prostate cancer treatment. Currently, researchers are exploring the role of the JTB gene in treating prostate cancer and have discovered its potential in treating prostate cancer and as a drug target.

Therapeutic potential of JTB genes

The therapeutic potential of the JTB gene is well documented. Studies have shown that inhibition of the JTB gene can significantly inhibit the progression and invasion of prostate cancer. In addition, inhibition of the JTB gene can significantly improve patients' quality of life.

Biological significance of JTB gene

The biological significance of the JTB gene lies in its expression level in rat prostate cancer cells and its regulatory effect on the growth and progression of prostate cancer cells. These findings provide important clues for studying the role of JTB genes in prostate cancer treatment.

in conclusion

The JTB gene is one of the genes with the highest expression in rat prostate cancer cells and is closely related to the incidence and mortality of prostate cancer. The protein encoded by the JTB gene is a transcription factor that plays an important role in various cancers. Like many cancers, the incidence and mortality of prostate cancer increase significantly in older men, and the expression levels of the JTB gene are related to age and sex. In recent years, researchers have conducted in-depth studies on the function of the JTB gene and discovered its potential in treating prostate cancer and as a drug target. Research on drug targets of the JTB gene is a hot topic in the field of prostate cancer treatment. Its biological significance lies in its expression level in rat prostate cancer cells and its regulatory effect on the growth and progression of prostate cancer cells.

Protein Name: Jumping Translocation Breakpoint

Functions: Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity)

The "JTB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about JTB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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