Target Name: SLITRK1
NCBI ID: G114798
Review Report on SLITRK1 Target / Biomarker Content of Review Report on SLITRK1 Target / Biomarker
SLITRK1
Other Name(s): SLIT and NTRK like family member 1, transcript variant 1 | KIAA1910 | SLIT and NTRK-like protein 1 | SLIT and NTRK like family member 1 | TTM | SLITRK1 variant 1 | SLIK1_HUMAN | leucine-rich repeat-containing protein 12 | Leucine rich repeat containing 12 | Leucine-rich repeat-containing protein 12 | LRRC12 | slit and trk like gene 1 | KIAA0918

SLITRK1: A Potential Drug Target and Biomarker

SLITRK1, short for short for SLIT and NTRK-like family member 1, is a gene that has been identified as a potential drug target and biomarker. The SLITRK1 gene is located on chromosome 12q13 and encodes a protein known as SLITRK1, which is a key regulator of microRNA (miRNA) expression.

Recent studies have shown that SLITRK1 plays a critical role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.SLITRK1 has also been implicated in the regulation of stem cell proliferation and differentiation, which could have implications for the development of cancer therapies.

SLITRK1 has also been shown to be involved in the regulation of inflammation, which could be a potential target for anti-inflammatory therapies.Studies have shown that SLITRK1 can modulate the expression of genes involved in inflammation and immune response, including the expression of genes involved in the production of pro-inflammatory cytokines.

SLITRK1 has also been shown to be involved in the regulation of cell survival and death, which could be a potential target for therapies aimed at extending lifespan or reducing the risk of disease.Studies have shown that SLITRK1 can modulate the expression of genes involved in cell survival and death, including the expression of genes involved in the production of apoptosis-promoting factors.

SLITRK1 has also been shown to be involved in the regulation of gene expression in a variety of organisms, including humans.Studies have shown that SLITRK1 can modulate the expression of genes involved in a wide range of biological processes, including cell division, growth, and differentiation, as well as metabolism and stress response.

Given the potential involvement of SLITRK1 in a wide range of biological processes, it is a promising target for drug development.Studies have shown that SLITRK1 can be effectively targeted with small molecules, including inhibitors ofSLITRK1-associated proteins and modulators ofSLITRK1-associated miRNAs.

In addition to its potential as a drug target, SLITRK1 has also been identified as a potential biomarker.Studies have shown thatSLITRK1 levels can be accurately measured using a variety of techniques, including qRT-PCR and Western blotting.These studies suggest that SLITRK1 may be a useful biomarker for the diagnosis and prognosis of various diseases.

Overall, SLITRK1 is a gene that has the potential to be a drug target and biomarker. Further research is needed to fully understand its role in various biological processes and to develop effective therapies based on its modulation.

Protein Name: SLIT And NTRK Like Family Member 1

Functions: It is involved in synaptogenesis and promotes excitatory synapse differentiation (PubMed:27273464, PubMed:27812321). Enhances neuronal dendrite outgrowth (PubMed:16224024, PubMed:19640509)

The "SLITRK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLITRK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SLITRK2 | SLITRK3 | SLITRK4 | SLITRK5 | SLITRK6 | SLK | SLMAP | SLMO2-ATP5E | SLN | SLPI | SLTM | SLU7 | SLURP1 | SLURP2 | SLX1A | SLX1A-SULT1A3 | SLX1B | SLX1B-SULT1A4 | SLX4 | SLX4IP | SLX9 | SMAD | SMAD1 | SMAD1-AS1 | SMAD1-AS2 | SMAD2 | SMAD3 | SMAD4 | SMAD5 | SMAD5-AS1 | SMAD6 | SMAD7 | SMAD9 | SMAGP | Small Conductance Calcium-Activated Potassium Channel (SK) | SMAP1 | SMAP2 | SMARCA1 | SMARCA2 | SMARCA4 | SMARCA5 | SMARCAD1 | SMARCAD1-DT | SMARCAL1 | SMARCAL1-AS1 | SMARCB1 | SMARCC1 | SMARCC2 | SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 | SMC1A | SMC1B | SMC2 | SMC2-DT | SMC3 | SMC4 | SMC5 | SMC5-DT | SMC5-SMC6 Complex | SMC6 | SMCHD1 | SMCO1 | SMCO2 | SMCO3 | SMCO4 | SMCP | SMCR2 | SMCR5 | SMCR8 | SMDT1 | SMG1 | SMG1P1 | SMG1P2 | SMG1P3 | SMG1P4 | SMG1P5 | SMG5 | SMG6 | SMG7 | SMG7-AS1 | SMG8 | SMG9 | SMILR | SMIM1 | SMIM10 | SMIM10L1 | SMIM10L2A | SMIM10L2B | SMIM11 | SMIM12 | SMIM13 | SMIM14 | SMIM15 | SMIM17 | SMIM18 | SMIM19 | SMIM2 | SMIM2-AS1