SLC18B1: A Protein Implicated in Disaccharide Maltoside Transport and Disease

Target Name: SLC18B1

NCBI ID: G116843

SLC18B1

SLC18B1: A Protein Implicated in Disaccharide Maltoside Transport and Disease

SLC18B1, also known as SLC18B1 gene, is a member of the Solute carrier family 18 that is located on chromosome 18. This gene is responsible for the production of a protein known as SLC18B1, which is a carrier protein for a type of sugar called disaccharide maltoside.

Disaccharide maltoside is a type of carbohydrate that is commonly found in many fruits and vegetables, as well as in certain dietary supplements. It is made up of two sugar molecules joined together, and it has a sweet taste.

SLC18B1 is the protein that is responsible for carrying disaccharide maltoside across cell membranes. It works by using its electrostatic properties to attract positively charged molecules to the surface of the membrane, where they can be absorbed into the cell.

Research has suggested that SLC18B1 may be a drug target or biomarker for several different diseases. For example, SLC18B1 has been shown to be involved in the development of certain neurological conditions, such as Alzheimer's disease and Parkinson's disease. It may also be involved in the development of certain cancers, such as breast cancer.

In addition to its potential as a drug target or biomarker, SLC18B1 has also been shown to have potential as a diagnostic tool. For example, researchers have used SLC18B1 as a marker to track the progression of certain diseases, such as cancer.

Overall, SLC18B1 is a protein that is involved in a variety of cellular processes, and it has potential as a drug target or biomarker for several different diseases. Further research is needed to fully understand its role in these processes and to determine its potential as a diagnostic tool.

Protein Name: Solute Carrier Family 18 Member B1

Functions: Proton-coupled polyamine antiporter involved in the translocation of polyamines from cytosol into secretory vesicles prior to their release via exocytosis. Uses the electrochemical proton gradient generated by a V-type proton-pumping ATPase to couple the efflux of protons with the uptake of a polyamine molecule (PubMed:25355561). Facilitates vesicular storage of spermine and spermidine in astrocytes with an impact on glutamatergic neuronal transmission and memory formation (PubMed:25355561) (By similarity). Upon antigen stimulation, regulates polyamine accumulation and release in mast cell secretory granules, which in turn potentiates mast cell degranulation and histamine secretion (By similarity)

The "SLC18B1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC18B1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets