WFIKKN2: Potential Drug Target and Biomarker (G124857)
WFIKKN2: Potential Drug Target and Biomarker
WFIKKN2 (WAP, FS, Ig, two KU and NTR module related protein) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidney. It is a member of the WAP (Wnt-associated protein) family, which is known for its role in development and maintenance of various tissues during embryonic development and throughout life. WFIKKN2 has been shown to play a role in several biological processes, including cell signaling, angiogenesis, and inflammation.
The protein encoded by the WFIKKN2 gene is a 21-kDa protein that consists of 191 amino acid residues. It has a unique structure that is composed of a single transmembrane domain and an intracellular tail region. The transmembrane domain of WFIKKN2 is rich in conserved epitopes, including a putative cytoplasmic domain and a transmembrane region that is involved in the protein's stability and interactions with other cellular components. The intracellular tail region of WFIKKN2 is composed of a unique domain that is involved in the protein's interaction with the endoplasmic reticulum (ER) and may be involved in the regulation of its stability.
WFIKKN2 has been shown to play a role in several biological processes, including cell signaling, angiogenesis, and inflammation. One of the most well-studied functions of WFIKKN2 is its role in cell signaling. WFIKKN2 has been shown to be involved in several signaling pathways, including the Wnt/FGF signaling pathway, the TGF-β signaling pathway, and the NF-kappa-B signaling pathway.
In addition to its role in cell signaling, WFIKKN2 has also been shown to be involved in the regulation of angiogenesis. Angiogenesis is the process by which new blood vessels are formed during embryonic development and throughout life. WFIKKN2 has been shown to play a role in the regulation of angiogenesis by promoting the migration of blood vessels and by controlling the growth and differentiation of blood vessels.
WFIKKN2 has also been shown to be involved in the regulation of inflammation. Inflammation is a critical immune response that helps to protect the body against infection and disease. WFIKKN2 has been shown to play a role in the regulation of inflammation by promoting the production of pro-inflammatory cytokines and by regulating the expression of anti-inflammatory cytokines.
Drug targeting and biomarker potential
WFIKKN2 has been shown to be a potential drug target in several diseases. For example, several studies have shown that inhibition of WFIKKN2 can reduce the production of pro-inflammatory cytokines and improve the production of anti-inflammatory cytokines, which could have implications for the treatment of inflammatory diseases such as heart disease, cancer, and autoimmune disorders.
In addition to its potential as a drug target, WFIKKN2 has also been shown to be a potential biomarker for several diseases. For example, several studies have shown that increased expression of WFIKKN2 is associated with the development of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Additionally, studies have shown that decreased expression of WFIKKN2 is associated with the progression of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
Conclusion
WFIKKN2 is a protein that has been shown to play a role in several biological processes, including cell signaling, angiogenesis, and inflammation. Its unique structure and multiple functions make it a potential drug target and biomarker for several diseases. Further research is needed to fully understand the role of WFIKKN2 in
Protein Name: WAP, Follistatin/kazal, Immunoglobulin, Kunitz And Netrin Domain Containing 2
Functions: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity)
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• expression level;
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More Common Targets
WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY | XKRYP7 | XLOC_007697 | XLOC_008559 | XLOC_009911 | XNDC1N | XPA | XPC | XPC complex
