MISP: A Protein Involved in Cell Division and Cancer Development

Target Name: MISP

NCBI ID: G126353

MISP

MISP: A Protein Involved in Cell Division and Cancer Development

MISP (Mitotic Spindle Positioning Protein) is a protein that plays a crucial role in the proper functioning of mitosis, the process by which a cell divides. MISP is a key component of the mitotic spindle, which is a structure that pulls the chromosomes apart during the cell division process.

MISP has been identified as a potential drug target and biomarker for a variety of diseases, including cancer. Its role in the development and progression of cancer, as well as its potential as a therapeutic agent, makes it an important topic of study.

MISP is a protein that is expressed in a wide range of tissues and cells throughout the body. It is highly conserved, with a high degree of sequence identity across different species. MISP is localized to the cytoplasm of the cell and is involved in the organization and stability of the mitotic spindle.

The mitotic spindle is a complex structure that is composed of multiple proteins that help to pull the chromosomes apart during the cell division process. MISP is one of the key proteins that helps to maintain the stability of the spindle and ensure that it functions properly.

MISP plays a crucial role in the regulation of the mitotic spindle. It helps to keep the spindle organized and stable, allowing it to properly pull the chromosomes apart during the cell division process. MISP also helps to ensure that the spindle is properly positioned and that the chromosomes are properly divided.

MISP is also involved in the regulation of the cytoskeleton. It helps to keep the cytoskeleton organized and stable, allowing it to support the cell and help it maintain its shape. MISP is also involved in the regulation of the actin cytoskeleton, which is the cytoskeleton that lies beneath the plasma membrane.

MISP is a protein that is expressed in a wide range of tissues and cells throughout the body. It is highly conserved, with a high degree of sequence identity across different species. This makes it a promising candidate for use as a drug or biomarker.

In addition to its role in the regulation of the mitotic spindle, MISP is also involved in the regulation of a variety of other cellular processes. It is involved in the regulation of cell adhesion, the process by which cells stick together and form tissues, as well as the regulation of cell signaling.

MISP is also involved in the regulation of the cytoskeleton. It helps to keep the cytoskeleton organized and stable, allowing it to support the cell and help it maintain its shape. MISP is also involved in the regulation of the actin cytoskeleton, which is the cytoskeleton that lies beneath the plasma membrane.

In conclusion, MISP is a protein that plays a crucial role in the functioning of mitosis and the regulation of the cytoskeleton. Its role in the development and progression of cancer, as well as its potential as a therapeutic agent, makes it an important topic of study. Further research is needed to fully understand the role of MISP in these processes and to develop safe and effective drugs or biomarkers based on it.

Protein Name: Mitotic Spindle Positioning

Functions: Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytospkeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus

The "MISP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MISP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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