ENPP6: A Potential Drug Target and Biomarker (G133121)

Target Name: ENPP6

NCBI ID: G133121

ENPP6

ENPP6: A Potential Drug Target and Biomarker

ENPP6 (ENP-6) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a key regulator of phospholipid metabolism and has been implicated in a number of diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders. In recent years, researchers have been interested in developing ENPP6 as a drug target or biomarker for a variety of diseases.

One of the unique features of ENPP6 is its role in modulating lipid metabolism. Lipid metabolism is the process by which the body produces and consumes energy, and it is a critical regulator of overall health and disease. ENPP6 is involved in the metabolism of different types of lipids, including cholesterol, triglycerides, and fatty acids. It has been shown to play a key role in the regulation of lipid metabolism and has been linked to a number of diseases, including cardiovascular disease and obesity.

In addition to its role in lipid metabolism, ENPP6 has also been shown to be involved in a number of other important biological processes. For example, it has been shown to play a key role in the regulation of cellular signaling, particularly in the signaling pathway known as the TGF-β pathway. The TGF-β pathway is a critical regulator of cell growth, differentiation, and survival, and it is involved in the development and maintenance of tissues and organs. ENPP6 has been shown to be involved in the regulation of TGF-β signaling and has been linked to a number of diseases, including cancer.

Another promising aspect of ENPP6 is its potential as a drug target. ENPP6 has been shown to be involved in a number of diseases and disorders, including cardiovascular disease, diabetes, and neurodegenerative disorders. It is thought that by targeting ENPP6, researchers may be able to develop new treatments for these diseases. For example, researchers have shown that ENPP6 is involved in the regulation of cellular signaling and that it plays a key role in the development and maintenance of tissues and organs. This suggests that targeting ENPP6 may be a promising way to develop new treatments for a variety of diseases.

In addition to its potential as a drug target, ENPP6 has also been shown to be a potential biomarker for a number of diseases. By measuring the level of ENPP6 in tissues or fluids, researchers may be able to monitor the effectiveness of treatments for diseases and disorders. For example, researchers have shown that ENPP6 levels are often reduced in the blood and tissues of individuals with cardiovascular disease, and that this may be a potential biomarker for this disease. Similarly, ENPP6 has been shown to be involved in the regulation of lipid metabolism and has been linked to a number of diseases, including obesity. By measuring the level of ENPP6 in tissues or fluids, researchers may be able to monitor the effectiveness of treatments for obesity and other diseases.

Overall, ENPP6 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Its role in modulating lipid metabolism and its involvement in the regulation of cellular signaling make it a promising candidate for targeting with new treatments. Further research is needed to fully understand the role of ENPP6 in disease and to develop effective treatments based on this protein.

Protein Name: Ectonucleotide Pyrophosphatase/phosphodiesterase 6

Functions: Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells (PubMed:15788404). Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity)

The "ENPP6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENPP6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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